Rabin, M., Birnbaum, D., Young, D., Birchmeier, C., Wigler, M. H., Ruddle, F. H. (July 1987) Human ROS1 and MAS1 oncogenes located in regions of chromosome 6 associated with tumor-specific rearrangements. Oncogene Res, 1 (2). pp. 169-78. ISSN 0890-6467 (Print)
Abstract
Oncogenes have been implicated in tumorigenesis based on their localization to chromosomal sites associated with tumor-specific structural rearrangements. We have mapped the human ros1 (formerly mcf3) and mas1 oncogenes to the distal half of chromosome 6q, within a region frequently rearranged in malignant cells. Chromosomal mapping of these two new human transforming genes may help elucidate the involvement of the long arm of chromosome 6 in diverse tumor types.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Cell Line Chromosome Mapping Chromosomes Human, Pair 6 Genes ras Humans Leukemia genetics Neoplasms genetics Nucleic Acid Hybridization Oncogenes |
| Subjects: | bioinformatics > genomics and proteomics > annotation > map annotation bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosome bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosomes, structure and function > chromosome bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > genes: types > oncogene |
| CSHL Authors: | |
| Communities: | CSHL labs > Wigler lab |
| Depositing User: | CSHL Librarian |
| Date: | July 1987 |
| Date Deposited: | 05 Apr 2012 18:25 |
| Last Modified: | 24 Feb 2017 21:44 |
| URI: | https://repository.cshl.edu/id/eprint/26019 |
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