A click chemistry approach to C3 symmetric, G-quadruplex stabilising ligands.

Moses, John E, Ritson, Dougal J, Zhang, Fengzhi, Lombardo, Caterina Maria, Haider, Shozeb, Oldham, Neil, Neidle, Stephen (June 2010) A click chemistry approach to C3 symmetric, G-quadruplex stabilising ligands. Organic and Biomolecular Chemistry, 8 (13). pp. 2926-2930. ISSN 1477-0520

Abstract

Described is the structure-based design and synthesis of a series of tris-triazole G-quadruplex binding ligands utilising the copper catalysed azide-alkyne 'click' reaction. The results of G-quadruplex stabilisation by the ligands are reported and discussed.

Item Type: Paper
Subjects: chemistry
CSHL Authors:
Communities: CSHL labs > Moses lab
SWORD Depositor: CSHL Elements
Depositing User: CSHL Elements
Date: 28 June 2010
Date Deposited: 02 Jul 2021 14:01
Last Modified: 02 Jul 2021 14:01
URI: https://repository.cshl.edu/id/eprint/40240

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