A click chemistry approach to C3 symmetric, G-quadruplex stabilising ligands.

Moses, John E, Ritson, Dougal J, Zhang, Fengzhi, Lombardo, Caterina Maria, Haider, Shozeb, Oldham, Neil, Neidle, Stephen (June 2010) A click chemistry approach to C3 symmetric, G-quadruplex stabilising ligands. Organic and Biomolecular Chemistry, 8 (13). pp. 2926-2930. ISSN 1477-0520

URL: https://www.ncbi.nlm.nih.gov/pubmed/20498912

DOI: 10.1039/c005055e

Abstract

Described is the structure-based design and synthesis of a series of tris-triazole G-quadruplex binding ligands utilising the copper catalysed azide-alkyne 'click' reaction. The results of G-quadruplex stabilisation by the ligands are reported and discussed.

Item Type:	Paper
Subjects:	chemistry
CSHL Authors:	Moses, John E.
Communities:	CSHL labs > Moses lab
SWORD Depositor:	CSHL Elements
Depositing User:	CSHL Elements
Date:	28 June 2010
Date Deposited:	02 Jul 2021 14:01
Last Modified:	02 Jul 2021 14:01
URI:	https://repository.cshl.edu/id/eprint/40240

Actions (login required)

Administrator's edit/view item