van Kempen, J., Gieselmann, M. A., Boyd, M., Steinmetz, N. A., Moore, T., Engel, T. A., Thiele, A. (December 2020) Top-down coordination of local cortical state during selective attention. Neuron. ISSN 0896-6273
Abstract
Spontaneous fluctuations in cortical excitability influence sensory processing and behavior. These fluctuations, long thought to reflect global changes in cortical state, were recently found to be modulated locally within a retinotopic map during spatially selective attention. We report that periods of vigorous (On) and faint (Off) spiking activity, the signature of cortical state fluctuations, are coordinated across brain areas with retinotopic precision. Top-down attention enhanced interareal local state coordination, traversing along the reverse cortical hierarchy. The extent of local state coordination between areas was predictive of behavioral performance. Our results show that cortical state dynamics are shared across brain regions, modulated by cognitive demands and relevant for behavior.
Item Type: | Paper |
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Subjects: | organism description > animal behavior > attention neurobiology > neuroscience organism description > animal behavior > vision |
CSHL Authors: | |
Communities: | CSHL labs > Engel lab |
Depositing User: | Matthew Dunn |
Date: | 30 December 2020 |
Date Deposited: | 11 Jan 2021 17:30 |
Last Modified: | 29 Jun 2021 17:52 |
PMCID: | PMC7927916 |
Related URLs: | |
URI: | https://repository.cshl.edu/id/eprint/39885 |
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