Single-Pass vs 2-Pass Endoscopic Ultrasound-Guided Fine-Needle Biopsy Sample Collection for Creation of Pancreatic Adenocarcinoma Organoids

LaComb, J. F., Plenker, D., Tiriac, H., Bucobo, J. C., D'Souza, L.S., Khokhar, A.S., Patel, H., Channer, B., Joseph, D., Wu, M., Tuveson, D. A., Li, E., Buscaglia, J. M. (February 2020) Single-Pass vs 2-Pass Endoscopic Ultrasound-Guided Fine-Needle Biopsy Sample Collection for Creation of Pancreatic Adenocarcinoma Organoids. Clin Gastroenterol Hepatol. ISSN 1542-3565

Abstract

Pancreatic ductal adenocarcinoma (PDAC) has one of the poorest prognoses of all malignancies, with a 5-year survival rate <8%.1,2 Suspicious lesions are typically diagnosed via endoscopic ultrasound-guided fine-needle aspiration or endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB).3 Fewer needle passes decreases the risk of postprocedure complications, including pancreatitis and hemorrhage, while allowing additional needle passes to be used for adjuvant tissue testing, such as organoid creation and DNA sequencing.

Item Type:	Paper
Subjects:	diseases & disorders > cancer diseases & disorders > cancer > cancer types > pancreatic cancer
CSHL Authors:	Tuveson, David A. Plenker, Dennis Tiriac, Herve Patel, Hardik
Communities:	CSHL labs > Tuveson lab CSHL Cancer Center Program > Cellular Communication in Cancer Program
Depositing User:	Adrian Gomez
Date:	29 February 2020
Date Deposited:	02 Apr 2020 19:49
Last Modified:	29 Jun 2021 15:43
PMCID:	PMC7483221
Related URLs:	Publisher
URI:	https://repository.cshl.edu/id/eprint/39222

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