Michael Wigler (June 1994) DNA sequence encoding mas onhcogene, polypeptides encoded therefrom and diagnostic and other methods based therefrom. United States Patent 5320941. .
Abstract
This invention provides a DNA sequence comprising an activated oncogene, said oncogene encoding a polypeptide capable of transforming NIH3T3 cells and of inducing a tumor when injected into nude mice, said DNA sequence having a nucleotide sequence substantially as shown in FIGS. 3A and 3B. The invention also concerns a polypeptide molecule encoded by an activated oncogene, said molecule having the properties of transforming NIH3T3 cells and of inducing a tumor when injected into nude mice and further said polypeptide having an amino acid sequence substantially as shown in FIGS. 3A and 3B. Finally, this invention provides a method for treating a tumor induced by an activated mas oncogene.
| Item Type: | Patent |
|---|---|
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > polypeptides |
| CSHL Authors: | |
| Communities: | CSHL labs > Wigler lab |
| Depositing User: | Matt Covey |
| Date: | 14 June 1994 |
| Date Deposited: | 13 Mar 2014 16:41 |
| Last Modified: | 13 Mar 2014 16:41 |
| URI: | https://repository.cshl.edu/id/eprint/29639 |
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