Homolog interaction during meiotic prophase I in Arabidopsis requires the SOLO DANCERS gene encoding a novel cyclin-like protein

Azumi, Y., Liu, D. H., Zhao, D. Z., Li, W. X., Wang, G. F., Hu, Y., Ma, H. (June 2002) Homolog interaction during meiotic prophase I in Arabidopsis requires the SOLO DANCERS gene encoding a novel cyclin-like protein. Embo Journal, 21 (12). pp. 3081-3095. ISSN 0261-4189

URL: http://www.ncbi.nlm.nih.gov/pubmed/12065421
DOI: 10.1093/emboj/cdf285

Abstract

Interactions between homologs in meiotic prophase I, such as recombination and synapsis, are critical for proper homolog segregation and involve the coordination of several parallel events. However, few regulatory genes have been identified; in particular, it is not clear what roles the proteins similar to the mitotic cell cycle regulators might play during meiotic prophase I. We describe here the isolation and characterization of a new Arabidopsis mutant called solo dancers that exhibits a severe defect in homolog synapsis, recombination and bivalent formation in meiotic prophase I, subsequently resulting in seemingly random chromosome distribution and formation of abnormal meiotic products. We further demonstrate that the mutation affects a meiosis-specific gene encoding a novel protein of 578 amino acid residues with up to 31% amino acid sequence identity to known cyclins in the C-terminal portion. These results argue strongly that homolog interactions during meiotic prophase I require a novel meiosis-specific cyclin in Arabidopsis.

Item Type: Paper
Subjects: organism description > plant > Arabidopsis
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
organs, tissues, organelles, cell types and functions > organelles, types and functions > meiosis
organism description > plant
CSHL Authors:
Communities: Watson School
Depositing User: Matt Covey
Date: June 2002
Date Deposited: 09 Jan 2014 15:17
Last Modified: 09 Jan 2014 15:17
PMCID: PMC126045
Related URLs:
URI: http://repository.cshl.edu/id/eprint/28665

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving