Oscillations of local field potentials in the rat dorsal striatum during spontaneous and instructed behaviors

DeCoteau, W. E., Thorn, C., Gibson, D. J., Courtemanche, R., Mitra, P. P., Kubota, Y., Graybiel, A. M. (May 2007) Oscillations of local field potentials in the rat dorsal striatum during spontaneous and instructed behaviors. Journal of Neurophysiology, 97 (5). pp. 3800-3805. ISSN 0022-3077

URL: https://www.ncbi.nlm.nih.gov/pubmed/17329629
DOI: 10.1152/jn.00108.2007

Abstract

Oscillatory activity is a candidate mechanism for providing frequency coding for the generation, storage and replay of sequential representations of events and episodes. We recorded local field potentials (LFPs) and spike activity in the striatum, a basal ganglia structure implicated in behavioral action-sequence learning and performance, as rats engaged in spontaneous and instructed behaviors in a T-maze task. We found that during voluntary behaviors, striatal LFPs exhibit prominent theta-band oscillations together with rhythms at higher and lower frequencies. Analysis of the theta-band activity demonstrated that these oscillations are strongly modulated during task performance and increase as the animals choose and execute their turning responses in the cue-instructed T-maze task. These theta rhythms are locally generated and are coherent across large parts of the striatum. We suggest that modulation of oscillatory activity in the striatum may be a key feature of neural processing related to the control of voluntary behavior.

Item Type: Paper
Uncontrolled Keywords: Animals Behavior, Animal Corpus Striatum/physiology Electroencephalography/methods Learning Male Maze Learning Rats Rats, Sprague-Dawley Spectrum Analysis Theta Rhythm Wakefulness HIPPOCAMPAL THETA RHYTHM EXTERNAL GLOBUS-PALLIDUS PRIMATE BASAL GANGLIA SUBTHALAMIC NUCLEUS IN-VIVO TEMPORAL STRUCTURE ACTIVITY PATTERNS PATH-INTEGRATION NEURONS MEMORY
Subjects: organism description > animal behavior
Investigative techniques and equipment > electrophysiology
organism description > animal behavior > learning
organism description > animal behavior > memory
organism description > animal > mammal > rodent > rat
organism description > animal > mammal > rodent > rat

organs, tissues, organelles, cell types and functions > tissues types and functions > striatum
CSHL Authors:
Communities: CSHL labs > Mitra lab
Depositing User: CSHL Librarian
Date: May 2007
Date Deposited: 30 Nov 2011 19:59
Last Modified: 03 Feb 2017 16:43
Related URLs:
URI: http://repository.cshl.edu/id/eprint/22995

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