Items where Community is "Dos Santos lab"

Lewis, Steven M, Dos Santos, Camila (November 2024) Epigenetic scars of Brca1 loss point toward breast cancer cell of origin. Nature Genetics. ISSN 1061-4036

Anandan, Dhivyaa, Trousdell, Marygrace, Somasundara, Amritha Varshini Hanasoge, dos Santos, Camila (November 2024) Determining the immunologic basis of pregnancy-induced oncoprotection in BRCA1 hereditary breast cancer. In: Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer and 2024 Winter Meeting.

Maia-Silva, Diogo, Cunniff, Patrick J, Schier, Allison C, Skopelitis, Damianos, Trousdell, Marygrace C, Moresco, Philip, Gao, Yuan, Kechejian, Vahag, He, Xue-Yan, Sahin, Yunus, Wan, Ledong, Alpsoy, Aktan, Liverpool, Jynelle, Krainer, Adrian R, Egeblad, Mikala, Spector, David L, Fearon, Douglas T, Dos Santos, Camila O, Taatjes, Dylan J, Vakoc, Christopher R (June 2024) Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma. Nature Genetics. ISSN 1061-4036

Henry, Samantha, Lewis, Steven Macauley, Cyrill, Samantha Leeanne, Callaway, Mackenzie Kate, Chatterjee, Deeptiman, Hanasoge Somasundara, Amritha Varshini, Jones, Gina, He, Xue-Yan, Caligiuri, Giuseppina, Ciccone, Michael Francis, Diaz, Isabella Andrea, Biswas, Amelia Aumalika, Hernandez, Evelyn, Ha, Taehoon, Wilkinson, John Erby, Egeblad, Mikala, Tuveson, David Arthur, Dos Santos, Camila Oresco (April 2024) Host response during unresolved urinary tract infection alters female mammary tissue homeostasis through collagen deposition and TIMP1. Nature Communications, 15 (1). p. 3282. ISSN 2041-1723 (Public Dataset)

Henry, Samantha, Lewis, Steven Macauley, Cyrill, Samantha Leeanne, Callaway, Mackenzie Kate, Chatterjee, Deeptiman, Hanasoge Somasundara, Amritha Varshini, Jones, Gina, He, Xue-Yan, Caligiuri, Giuseppina, Ciccone, Michael Francis, Diaz, Isabella Andrea, Biswas, Amelia, Hernandez, Evelyn, Ha, Taehoon, Wilkinson, John Erby, Egeblad, Mikala, Tuveson, David Arthur, Oresco dos Santos, Camila (February 2024) Host response during unresolved urinary tract infection alters mammary tissue homeostasis through collagen deposition and TIMP1. bioRxiv. (Public Dataset) (Submitted)

Patel, H, Zanos, T, Hewitt, DB (January 2024) Deep Learning Applications in Pancreatic Cancer. Cancers, 16 (2). p. 436. ISSN 2072-6694

Ortiz, Jenelys Ruiz, Lewis, Steven M, Ciccone, Michael F, Chatterjee, Deeptiman, Henry, Samantha, Siepel, Adam, Dos Santos, Camila O (September 2023) Single-cell transcription mapping of murine and human mammary organoids responses to female hormones. bioRxiv. (Public Dataset) (Submitted)

Yao, Min, Preall, Jonathan, Yeh, Johannes, Pappin, Darryl J, Cifani, Paolo, Zhao, Yixin, Shen, Sophia, Moresco, Philip, He, Brian, Patel, Hardik, Habowski, Amber N, King, Daniel A, Raphael, Kara L, Rishi, Arvind, Sejpal, Divyesh V, Weiss, Matthew, Tuveson, David, Fearon, Douglas T (September 2023) Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies to self-antigens. JCI Insight. e172449. ISSN 2379-3708 (Public Dataset)

Callaway, Mackenzie K, Dos Santos, Camila O (July 2023) Gestational Breast Cancer - a Review of Outcomes, Pathophysiology, and Model Systems. Journal of Mammary Gland Biology and Neoplasia, 28 (1). p. 16. ISSN 1083-3021

Costa, Iris Munhoz, Effer, Brian, Costa-Silva, Tales Alexandre, Chen, Chen, Ciccone, Michael F, Pessoa, Adalberto, Dos Santos, Camila O, Monteiro, Gisele (July 2023) Cathepsin B Is Not an Intrinsic Factor Related to Asparaginase Resistance of the Acute Lymphoblastic Leukemia REH Cell Line. International Journal of Molecular Sciences, 24 (13). p. 11215. ISSN 1661-6596

Ruiz-Ortiz, Jenelys (May 2023) Characterizing Models to Study Cellular Composition Changes in Response to Pregnancy Hormones in the Human Mammary Gland. PhD thesis, Cold Spring Harbor Laboratory.

Thacker, Gatha, Henry, Samantha, Nandi, Ajeya, Debnath, Rahul, Singh, Snahlata, Nayak, Anupma, Susnik, Barbara, Boone, Melinda M, Zhang, Qing, Kesmodel, Susan B, Gumber, Sanjeev, Das, Gokul M, Kambayashi, Taku, Dos Santos, Camila O, Chakrabarti, Rumela (March 2023) Immature natural killer cells promote progression of triple-negative breast cancer. Science Translational Medicine, 15 (686). eabl4414. ISSN 1946-6234

Chatterjee, Deeptiman, Deng, Wu-Min (2023) Standardization of Single-Cell RNA-Sequencing Analysis Workflow to Study Drosophila Ovary. Methods in Molecular Biology, 2677. pp. 151-171. ISSN 1064-3745

Hanasoge Somasundara, Amritha Varshini (November 2022) Investigating the role of changes to the mammary gland immune microenvironment in pregnancy-induced oncoprotection. PhD thesis, Cold Spring Harbor Laboratory.

Lewis, Steven M, Callaway, Mackenzie K, Dos Santos, Camila O (November 2022) Clinical applications of 3D normal and breast cancer organoids: A review of concepts and methods. Experimental Biology and Medicine. p. 15353702221131877. ISSN 1535-3702

Chatterjee, Deeptiman, Costa, Caique Almeida Machado, Wang, Xian-Feng, Jevitt, Allison, Huang, Yi-Chun, Deng, Wu-Min (November 2022) Single-cell transcriptomics identifies Keap1-Nrf2 regulated collective invasion in a Drosophila tumor model. eLife, 11. e80956. ISSN 2050-084X

Demyan, Lyudmyla, Habowski, Amber N, Plenker, Dennis, King, Daniel A, Standring, Oliver J, Tsang, Caitlin, St Surin, Luce, Rishi, Arvind, Crawford, James M, Boyd, Jeff, Pasha, Shamsher A, Patel, Hardik, Galluzzo, Zachary, Metz, Christine, Gregersen, Peter K, Fox, Sharon, Valente, Cristina, Abadali, Sonya, Matadial-Ragoo, Steffi, DePeralta, Danielle K, Deutsch, Gary B, Herman, Joseph M, Talamini, Mark A, Tuveson, David A, Weiss, Matthew J (September 2022) Pancreatic Cancer Patient-derived Organoids Can Predict Response to Neoadjuvant Chemotherapy. Annals of Surgery, 276 (3). pp. 450-462. ISSN 0003-4932

Lee, Bernett, Cyrill, Samantha Leeanne, Lee, Wendy, Melchiotti, Rossella, Andiappan, Anand Kumar, Poidinger, Michael, Rötzschke, Olaf (August 2022) Analysis of archaic human haplotypes suggests that 5hmC acts as an epigenetic guide for NCO recombination. BMC Biology, 20 (1). p. 173. ISSN 1741-7007

Soroka, Stanley, Plenker, Dennis, Patel, Hardik, Habowski, Amber, Tuveson, David, Martello-Rooney, Laura (2022) Characterization of gemcitabine- and paclitaxel-loaded poly(lactic-co-glycolic acid) microparticles as a treatment for pancreatic ductal adenocarcinoma using in vitro models. In: Annual Meeting of the American-Association-for-Cancer-Research (AACR), APR 08-13, 2022, New Orleans, LA.

Hanasoge Somasundara, Amritha Varshini, Moss, Matthew A, Feigman, Mary J, Chen, Chen, Cyrill, Samantha L, Ciccone, Michael F, Trousdell, Marygrace C, Vollbrecht, Macy, Li, Siran, Kendall, Jude, Beyaz, Semir, Wilkinson, John E, Dos Santos, Camila O (December 2021) Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis. Cell Reports, 37 (10). p. 110099. ISSN 2211-1247

Costa, Iris Munhoz, Moura, Debora Custodio, Lima, Guilherme Meira, Pessoa, Adalberto, dos Santos, Camila Oresco, de Oliveira, Marcos A, Monteiro, Gisele (October 2021) Engineered asparaginase from Erwinia chrysanthemi enhances asparagine hydrolase activity and diminishes enzyme immunoreactivity - a new promise to treat acute lymphoblastic leukemia. Journal of Chemical Technology and Biotechnology. ISSN 0268-2575

Zahid, Huda, Buchholz, Caroline R, Singh, Manjulata, Ciccone, Michael F, Chan, Alice, Nithianantham, Stanley, Shi, Ke, Aihara, Hideki, Fischer, Marcus, Schönbrunn, Ernst, Dos Santos, Camila O, Landry, Joseph W, Pomerantz, William CK (September 2021) New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition. Journal of Medicinal Chemistry. ISSN 0022-2623

Truong, Thu H, Benner, Elizabeth A, Hagen, Kyla M, Temiz, Nuri A, Kerkvliet, Carlos Perez, Wang, Ying, Cortes-Sanchez, Emilio, Yang, Chieh-Hsiang, Trousdell, Marygrace C, Pengo, Thomas, Guillen, Katrin P, Welm, Bryan E, Dos Santos, Camila O, Telang, Sucheta, Lange, Carol A, Ostrander, Julie H (June 2021) PELP1/SRC-3-dependent regulation of metabolic PFKFB kinases drives therapy resistant ER+ breast cancer. Oncogene. ISSN 0950-9232

Henry, Samantha, Trousdell, Marygrace C, Cyrill, Samantha L, Zhao, Yixin, Feigman, Mary J, Bouhuis, Julia M, Aylard, Dominik A, Siepel, Adam, Dos Santos, Camila O (May 2021) Characterization of Gene Expression Signatures for the Identification of Cellular Heterogeneity in the Developing Mammary Gland. Journal of Mammary Gland Biology and Neoplasia. ISSN 1083-3021

Ruiz-Ortiz, Jenelys, Tollkuhn, Jessica (January 2021) Specificity in sociogenomics: Identifying causal relationships between genes and behavior. Hormones and Behaviour, 127. p. 104882. ISSN 0018-506X

Ciccone, M. F., Trousdell, M. C., Dos Santos, C. O. (November 2020) Characterization of Organoid Cultures to Study the Effects of Pregnancy Hormones on the Epigenome and Transcriptional Output of Mammary Epithelial Cells. J Mammary Gland Biol Neoplasia, 25 (4). pp. 351-366. ISSN 1083-3021

Slepicka, P. F., Somasundara, A. V. H., Dos Santos, C. O. (October 2020) The molecular basis of mammary gland development and epithelial differentiation. Semin Cell Dev Biol. ISSN 1084-9521

Fein, Miriam R, He, Xue-Yan, Almeida, Ana S, Bružas, Emilis, Pommier, Arnaud, Yan, Ran, Eberhardt, Anaïs, Fearon, Douglas T, Van Aelst, Linda, Wilkinson, John Erby, Dos Santos, Camila O, Egeblad, Mikala (October 2020) Cancer cell CCR2 orchestrates suppression of the adaptive immune response. Journal of Experimental Medicine, 217 (10). ISSN 0022-1007

Feigman, Mary J, Moss, Matthew A, Chen, Chen, Cyrill, Samantha L, Ciccone, Michael, Trousdell, Marygrace, Yang, Shih Ting, Frey, Wesley D, Wilkinson, John E, dos Santos, Camila O (June 2020) Pregnancy reprograms the epigenome of mammary epithelial cells and blocks the development of premalignant mammary lesions in response to cMYC-overexpression. In: AACR Special Conference on the Evolving Landscape of Cancer Modeling.

Feigman, M.J., Moss, M.A., Chen, C., Cyrill, S.L., Cicone, M.F., Trousdell, M.C., Yang, S.-T., Frey, W.D., Wilkinson, J.E., Dos Santos, C. O. (May 2020) Pregnancy Reprograms the Epigenome of Mammary Epithelial Cells and Blocks the Development of Premalignant Lesions. Nat Commun, 11 (1). p. 2649. ISSN 2041-1723

Ibrahim, Ayman M, Moss, Matthew A, Gray, Zane, Rojo, Michelle D, Burke, Caitlin M, Schwertfeger, Kathryn L, Dos Santos, Camila O, Machado, Heather L (2020) Diverse Macrophage Populations Contribute to the Inflammatory Microenvironment in Premalignant Lesions During Localized Invasion. Frontiers in Oncology, 10. p. 569985. ISSN 2234-943X

Slepicka, P. F., Cyrill, S. L., Dos Santos, C. O. (July 2019) Pregnancy and Breast Cancer: Pathways to Understand Risk and Prevention. Trends Mol Med, 25 (10). pp. 866-881. ISSN 1471-4914

Kirberger, S. E., Ycas, P. D., Johnson, J. A., Chen, C., Ciccone, M. F., Woo, R. W. L., Urick, A. K., Zahid, H., Shi, K., Aihara, H., McAllister, S. D., Kashani-Sabet, M., Shi, J., Dickson, A., Dos Santos, C. O., Pomerantz, W. C. K. (February 2019) Selectivity, ligand deconstruction, and cellular activity analysis of a BPTF bromodomain inhibitor. Org Biomol Chem, 17 (2). pp. 2020-2027. ISSN 1477-0520

Fein, Miriam, He, Xue-Yan, Almeida, Ana, Bružas, Emilis, Pommier, Arnaud, Yan, Ran, Eberhardt, Anaïs, Fearon, Douglas, Van Aelst, Linda, Wilkinson, John, dos Santos, Camila, Egeblad, Mikala (August 2018) Cancer cell CCR2 orchestrates suppression of the adaptive immune response. bioRxiv.

Fein, M. R., He, X. Y., Almeida, A. S., Pommier, A., Bruzas, E., Eberhardt, A., Wilkinson, J. E., dos Santos, C., Egeblad, M. (May 2018) Targeting cancer cell CCR2 enhances synergistic immune surveillance in breast cancer. Cancer Research, 78 (10 Sup). pp. 75-76. ISSN 0008-5472

Fein, Miriam R, He, Xue-Yan, Almeida, Ana S, Pommier, Arnaud, Bruzas, Emilis, Eberhardt, Anais, Wilkinson, John Erby, dos Santos, Camila, Egeblad, Mikala (May 2018) Targeting cancer cell CCR2 enhances synergistic immune surveillance in breast cancer. In: Functional Annotation of Animal Genomes (FAANG) ASAS-ISAG Joint Symposium.

Frey, W. D., Chaudhry, A., Slepicka, P. F., Ouellette, A. M., Kirberger, S. E., Pomerantz, W. C. K., Hannon, G. J., Dos Santos, C. O. (July 2017) BPTF Maintains Chromatin Accessibility and the Self-Renewal Capacity of Mammary Gland Stem Cells. Stem Cell Reports, 9 (1). pp. 23-31. ISSN 2213-6711 (Public Dataset)

Urick, Andrew, Hawk, Laura, Cassel, Melissa, Mishra, Neeraj, Kirberger, Steven, Ycas, Peter, Dos Santos, Camila, Pomerantz, William (August 2016) Dual screening using protein-observed fluorine NMR uncovers the first selective inhibitor for BPTF. In: American Chemical Society.

Urick, A. K., Hawk, L. M., Cassel, M. K., Mishra, N. K., Liu, S., Adhikari, N., Zhang, W., Dos Santos, C. O., Hall, J. L., Pomerantz, W. C. (October 2015) Dual Screening of BPTF and Brd4 Using Protein-Observed Fluorine NMR Uncovers New Bromodomain Probe Molecules. ACS Chem Biol, 10 (10). pp. 2246-56. ISSN 1554-8937 (Electronic)1554-8929 (Linking)

Dos Santos, C. O., Dolzhenko, E., Hodges, E., Smith, A. D., Hannon, G. J. (May 2015) An Epigenetic Memory of Pregnancy in the Mouse Mammary Gland. Cell Reports. ISSN 2211-1247

Yu, Duonan, dos Santos, Camila O, Zhao, Guowei, Jiang, Jing, Amigo, Julio D, Khandros, Eugene, Dore, Louis C, Yao, Yu, D'Souza, Janine, Zhang, Zhe, Ghaffari, Saghi, Choi, John, Friend, Sherree, Tong, Wei, Orange, Jordan S, Paw, Barry H, Weiss, Mitchell J (August 2010) miR-451 protects against erythroid oxidant stress by repressing 14-3-3zeta. Genes and Development, 24 (15). pp. 1620-1633. ISSN 0890-9369

dos Santos, Camila O, Dore, Louis C, Valentine, Eric, Shelat, Suresh G, Hardison, Ross C, Ghosh, Manik, Wang, Wei, Eisenstein, Richard S, Costa, Fernando F, Weiss, Mitchell J (October 2008) An iron responsive element-like stem-loop regulates alpha-hemoglobin-stabilizing protein mRNA. Journal of Biological Chemistry, 283 (40). pp. 26956-26964. ISSN 0021-9258