Cancer During Pregnancy: Navigating Clinical and Research Challenges

Callaway, Mackenzie K, Comfort, Lizelle, Anandan, Dhivyaa, Sharma, Ruby, Florez, Narjust, Lyons, Traci R, Germain, Doris, Cho, Kathleen R, Rochelson, Burton L, Bonanno, Clarissa, Oktay, Kutluk, Roychoudhury, Sudarshana, O’donnell, Eileen, Barakat, Richard, Marquardt, Joanne, Bianchi, Diana W, Cardonick, Elyce, Norton, Larry, Partridge, Ann H, Domchek, Susan M, Borges, Virginia F, Amant, Frédéric, Dos Santos, Camila O (May 2026) Cancer During Pregnancy: Navigating Clinical and Research Challenges. Current Oncology, 33 (5). p. 296. ISSN 1718-7729

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Abstract

The incidence of cancer during pregnancy is rising, yet scientific understanding and clinical management remain underdeveloped. Delayed diagnoses, limited therapeutic options, and lack of safety data exacerbate the clinical challenges of treating cancer during pregnancy. Further, the biology of gestational cancers is poorly understood due to the scarcity of model systems and mechanistic studies. This manuscript presents a multidisciplinary perspective from a group of researchers and clinicians to evaluate the current state of pregnancy-associated cancers, identify unmet clinical and biological questions, and propose strategies to improve diagnosis, treatment, and maternal–fetal outcomes.

Item Type: Paper
Subjects: diseases & disorders > cancer
diseases & disorders
diseases & disorders > pregnancy
CSHL Authors:
Communities: CSHL labs > Dos Santos lab
CSHL Post Doctoral Fellows
SWORD Depositor: CSHL Elements
Depositing User: CSHL Elements
Date: 19 May 2026
Date Deposited: 22 May 2026 13:18
Last Modified: 22 May 2026 13:18
Related URLs:
URI: https://repository.cshl.edu/id/eprint/42212

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