Sun, Mengyi, McCandlish, David M (June 2025) Positive genetic interactions: high impact, but underrepresented in the literature. bioRxiv. ISSN 2692-8205 (Submitted)
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Abstract
Genetic interactions reveal functional relationships between genes and are classified as negative or positive. Negative interactions typically link genes with similar functional annotations, while positive interactions are often viewed as less informative and typically link genes that are less obviously related. Integrating yeast genetic interaction data with literature and citation metrics, we find that positive interactions are consistently associated with higher scientific impact yet remain underrepresented in the literature.
| Item Type: | Paper |
|---|---|
| Subjects: | bioinformatics bioinformatics > computational biology |
| CSHL Authors: | |
| Communities: | CSHL labs > McCandlish lab |
| SWORD Depositor: | CSHL Elements |
| Depositing User: | CSHL Elements |
| Date: | 27 June 2025 |
| Date Deposited: | 30 Jul 2025 12:23 |
| Last Modified: | 30 Jul 2025 12:23 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/41921 |
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