Spatial and temporal correlations in neural networks with structured connectivity

Shi, YL, Zeraati, R, Levina, A, Engel, TA (January 2023) Spatial and temporal correlations in neural networks with structured connectivity. Physical Review Research, 5 (1). ISSN 2643-1564

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Abstract

This article is part of the Physical Review Research collection titled Physics of Neuroscience. Correlated fluctuations in the activity of neural populations reflect the network's dynamics and connectivity. The temporal and spatial dimensions of neural correlations are interdependent. However, prior theoretical work mainly analyzed correlations in either spatial or temporal domains, oblivious to their interplay. We show that the network dynamics and connectivity jointly define the spatiotemporal profile of neural correlations. We derive analytical expressions for pairwise correlations in networks of binary units with spatially arranged connectivity in one and two dimensions. We find that spatial interactions among units generate multiple timescales in auto- and cross-correlations. Each timescale is associated with fluctuations at a particular spatial frequency, making a hierarchical contribution to the correlations. External inputs can modulate the correlation timescales when spatial interactions are nonlinear, and the modulation effect depends on the operating regime of network dynamics. These theoretical results open new ways to relate connectivity and dynamics in cortical networks via measurements of spatiotemporal neural correlations.

Item Type:	Paper
Subjects:	organs, tissues, organelles, cell types and functions > tissues types and functions > cerebral cortex organs, tissues, organelles, cell types and functions > tissues types and functions > neural networks organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons
CSHL Authors:	Engel, Tatiana Shi, Yan-Liang
Communities:	CSHL labs > Engel lab
SWORD Depositor:	CSHL Elements
Depositing User:	CSHL Elements
Date:	1 January 2023
Date Deposited:	17 Feb 2023 15:38
Last Modified:	03 Jul 2024 16:10
PMCID:	PMC11210526
URI:	https://repository.cshl.edu/id/eprint/40841

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