Pisupati, Sashank, Chartarifsky-Lynn, Lital, Khanal, Anup, Churchland, Anne K (January 2021) Lapses in perceptual decisions reflect exploration. eLife, 10. pp. 1-27. ISSN 2050-084X
![[thumbnail of Lapses in perceptual decisions reflect exploration.pdf]](https://repository.cshl.edu/style/images/fileicons/application_pdf.png) |
PDF
Lapses in perceptual decisions reflect exploration.pdf Download (1MB) |
Abstract
Perceptual decision-makers often display a constant rate of errors independent of evidence strength. These 'lapses' are treated as a nuisance arising from noise tangential to the decision, e.g. inattention or motor errors. Here, we use a multisensory decision task in rats to demonstrate that these explanations cannot account for lapses' stimulus dependence. We propose a novel explanation: lapses reflect a strategic trade-off between exploiting known rewarding actions and exploring uncertain ones. We tested this model's predictions by selectively manipulating one action's reward magnitude or probability. As uniquely predicted by this model, changes were restricted to lapses associated with that action. Finally, we show that lapses are a powerful tool for assigning decision-related computations to neural structures based on disruption experiments (here, posterior striatum and secondary motor cortex). These results suggest that lapses reflect an integral component of decision-making and are informative about action values in normal and disrupted brain states.
| Item Type: | Paper |
|---|---|
| Subjects: | organism description > animal organism description > animal behavior organism description > animal behavior > perception > cognition organism description > animal behavior > decision making organism description > animal > mammal organism description > animal behavior > perception organism description > animal > mammal > rodent > rat organism description > animal > mammal > rodent > rat organism description > animal > mammal > rodent |
| CSHL Authors: | |
| Communities: | CSHL labs > Churchland lab School of Biological Sciences > Publications |
| SWORD Depositor: | CSHL Elements |
| Depositing User: | CSHL Elements |
| Date: | 11 January 2021 |
| Date Deposited: | 29 Apr 2021 17:05 |
| Last Modified: | 25 Jan 2024 16:16 |
| PMCID: | PMC7846276 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/39950 |
Actions (login required)
 |
Administrator's edit/view item |