Spiteri, C., Mason, C., Zhang, F., Ritson, D. J., Sharma, P., Keeling, S., Moses, J. E. (June 2010) An efficient entry to 1,2-benzisoxazoles via 1,3-dipolar cycloaddition of in situ generated nitrile oxides and benzyne. Org Biomol Chem, 8 (11). pp. 2537-42. ISSN 1477-0520
DOI: 10.1039/b927235f
Abstract
An efficient protocol for the synthesis of a range of 1,2-benzisoxazoles using an improved 1,3-dipolar cycloaddition of nitrile oxides and benzyne is described. Key to the procedure is the in situ generation of the reactive nitrile oxide and benzyne reactants simultaneously.
| Item Type: | Paper |
|---|---|
| Additional Information: | 1477-0539 Spiteri, Christian Mason, Christopher Zhang, Fengzhi Ritson, Dougal J Sharma, Pallavi Keeling, Steve Moses, John E Journal Article Research Support, Non-U.S. Gov't England Org Biomol Chem. 2010 Jun 7;8(11):2537-42. doi: 10.1039/b927235f. Epub 2010 Apr 7. |
| Uncontrolled Keywords: | Benzene Derivatives/*chemistry Cyclization Isoxazoles/*chemical synthesis/chemistry Molecular Structure Nitriles/*chemistry Oxides/*chemistry ortho-Aminobenzoates/chemistry |
| CSHL Authors: | |
| Communities: | CSHL labs > Moses lab |
| Depositing User: | Matthew Dunn |
| Date: | 7 June 2010 |
| Date Deposited: | 19 Apr 2021 20:28 |
| Last Modified: | 19 Apr 2021 20:28 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/39545 |
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