Sharma, P., Moses, J. E. (June 2010) Ethynyldiisopropylsilyl: a new alkynylsilane protecting group and "click" linker. Org Lett, 12 (12). pp. 2860-3. ISSN 1523-7052
DOI: 10.1021/ol100968t
Abstract
A new silyl-based reagent has been developed for "catch and release" immobilization, combining click chemistry with silyl protection. The traditional "all carbon" attachment to solid supports in a silyl type linker was substituted with a stable triazole, easily assembled using the CuAAC reaction. The methodology introduces a novel ethynyldiiospropylchlorosilane reagent (EDIPS-Cl) as a functionalized protecting group linker.
| Item Type: | Paper |
|---|---|
| Additional Information: | Organic letters |
| CSHL Authors: | |
| Communities: | CSHL labs > Moses lab |
| Depositing User: | Matthew Dunn |
| Date: | 18 June 2010 |
| Date Deposited: | 19 Apr 2021 20:24 |
| Last Modified: | 19 Apr 2021 20:24 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/39542 |
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