Spiteri, C., Keeling, S., Moses, J. E. (August 2010) New synthesis of 1-substituted-1H-indazoles via 1,3-dipolar cycloaddition of in situ generated nitrile imines and benzyne. Org Lett, 12 (15). pp. 3368-71. ISSN 1523-7052
DOI: 10.1021/ol101150t
Abstract
A new synthesis of 1-substituted-1H-indazoles via 1,3-dipolar cycloaddition of nitrile imines to benzyne is described. The reaction is completed within 5 min, affording the corresponding N(1)-C(3) disubstituted indazoles in moderate to excellent yields.
| Item Type: | Paper |
|---|---|
| Additional Information: | Organic letters |
| Uncontrolled Keywords: | Benzene Derivatives/*chemistry Combinatorial Chemistry Techniques Cyclization Imines/*chemistry Indazoles/*chemical synthesis/chemistry Molecular Structure Nitriles/*chemistry |
| CSHL Authors: | |
| Communities: | CSHL labs > Moses lab |
| Depositing User: | Matthew Dunn |
| Date: | 6 August 2010 |
| Date Deposited: | 19 Apr 2021 20:23 |
| Last Modified: | 19 Apr 2021 20:23 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/39541 |
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