Nucleotide Sequence of the Bacterial Transposon Tn-1681 Encoding a Heat Stable Toxin and Its Identification in Entero Toxigenic Escherichia-Coli Strains

So, M., McCarthy, B. J. (1980) Nucleotide Sequence of the Bacterial Transposon Tn-1681 Encoding a Heat Stable Toxin and Its Identification in Entero Toxigenic Escherichia-Coli Strains. Proceedings of the National Academy of Sciences of the United States of America, 77 (7). pp. 4011-4015.

URL: https://pubmed.ncbi.nlm.nih.gov/6254008
DOI: 10.1073/pnas.77.7.4011

Abstract

The E. coli heat-stable toxin (ST I) is encoded within a transposon (Tn1681) flanked by inverted repeats of insertion sequence 1 (IS1). By subcloning restriction fragments and by insertion mutagenesis, the gene for ST I within the transposon was located precisely. The complete nucleotide sequence of the central portion of Tn1681 (i.e., that part flanked by IS1) was determined and the coding sequence of the toxin was identified.

Item Type: Paper
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > RNA regulation
organism description > bacteria > escherichia coli
Communities: Cold Spring Harbor Laboratory of Quantitative Biology
Depositing User: Elizabeth Pessala
Date: 1980
Date Deposited: 06 May 2020 20:26
Last Modified: 06 May 2020 20:26
PMCID: PMC349758
URI: https://repository.cshl.edu/id/eprint/39333

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