Lukey, M. J., Katt, W. P., Cerione, R. A. (May 2018) Targeting Therapy Resistance: When Glutamine Catabolism Becomes Essential. Cancer Cell, 33 (5). pp. 795-797. ISSN 1878-3686
Abstract
Identifying contexts in which cancer cells become addicted to specific nutrients is critical for developing targeted metabolic therapies. In this issue of Cancer Cell, Momcilovic et al. report that suppressed glycolysis following mTOR inhibition is countered by adaptive glutamine catabolism in lung squamous cell carcinoma, sensitizing tumors to glutaminase inhibition. Preview on: The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma. [Cancer Cell. 2018]
| Item Type: | Paper |
|---|---|
| Subjects: | diseases & disorders > cancer > drugs and therapies diseases & disorders > cancer > cancer types > lung cancer organs, tissues, organelles, cell types and functions > organs types and functions > metabolism |
| CSHL Authors: | |
| Communities: | CSHL labs > Lukey lab |
| Depositing User: | Adrian Gomez |
| Date: | 14 May 2018 |
| Date Deposited: | 28 Jan 2020 16:08 |
| Last Modified: | 15 Nov 2023 18:56 |
| PMCID: | PMC9062989 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/38938 |
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