Katt, W. P., Lukey, M. J., Cerione, R. A. (September 2019) Starving the Devourer: Cutting Cancer Off from Its Favorite Foods. Cell Chem Biol, 26 (9). pp. 1197-1199. ISSN 2451-9448
Abstract
Increased consumption of glucose and glutamine are metabolic hallmarks of tumorigenesis. In this issue of Cell Chemical Biology, Reckzeh et al. (2019) describe the discovery of Glutor, a potent inhibitor of cellular glucose uptake. Combining Glutor with the glutaminase inhibitor CB-839 creates a metabolic crisis in cancer cells, synergistically impeding proliferation.
| Item Type: | Paper |
|---|---|
| Subjects: | diseases & disorders > cancer diseases & disorders organs, tissues, organelles, cell types and functions > cell types and functions > cell functions organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > cell proliferation organs, tissues, organelles, cell types and functions > cell types and functions diseases & disorders > cancer > drugs and therapies organs, tissues, organelles, cell types and functions > organs types and functions > metabolism organs, tissues, organelles, cell types and functions |
| CSHL Authors: | |
| Communities: | CSHL labs > Lukey lab |
| Depositing User: | Adrian Gomez |
| Date: | 19 September 2019 |
| Date Deposited: | 27 Jan 2020 16:08 |
| Last Modified: | 02 Feb 2024 16:07 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/38933 |
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