Control of meristem determinacy by trehalose 6-phosphate phosphatases is uncoupled from enzymatic activity

Claeys, H., Vi, S. L., Xu, X., Satoh-Nagasawa, N., Eveland, A. L., Goldshmidt, A., Feil, R., Beggs, G. A., Sakai, H., Brennan, R. G., Lunn, J. E., Jackson, D. (April 2019) Control of meristem determinacy by trehalose 6-phosphate phosphatases is uncoupled from enzymatic activity. Nat Plants, 5 (4). pp. 352-357. ISSN 2055-0278

URL: https://www.ncbi.nlm.nih.gov/pubmed/30936436

DOI: 10.1038/s41477-019-0394-z

Abstract

Meristem fate is regulated by trehalose 6-phosphate phosphatases (TPPs), but their mechanism of action remains mysterious. Loss of the maize TPPs RAMOSA3 and TPP4 leads to reduced meristem determinacy and more inflorescence branching. However, analysis of an allelic series revealed no correlation between enzymatic activity and branching, and a catalytically inactive version of RA3 complements the ra3 mutant. Together with their nuclear localization, these findings suggest a moonlighting function for TPPs.

Item Type:	Paper
Subjects:	bioinformatics bioinformatics > genomics and proteomics > genetics & nucleic acid processing bioinformatics > genomics and proteomics organism description > plant > maize bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification organs, tissues, organelles, cell types and functions > tissues types and functions > meristem organs, tissues, organelles, cell types and functions organism description > plant bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > plant proteins bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types organs, tissues, organelles, cell types and functions > tissues types and functions
CSHL Authors:	Jackson, David P. Claeys, Hannes Vi, Son Lang Goldschmidt, Alexander Xu, Xiaosa
Communities:	CSHL labs > Jackson lab
Depositing User:	Matthew Dunn
Date:	1 April 2019
Date Deposited:	09 Apr 2019 15:15
Last Modified:	01 Feb 2024 21:04
PMCID:	PMC7444751
Related URLs:	Publisher
URI:	https://repository.cshl.edu/id/eprint/37769

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