The molecular basis for tropomyosin isoform diversity

Lees-Miller, J. P., Helfman, D. M. (September 1991) The molecular basis for tropomyosin isoform diversity. Bioessays, 13 (9). pp. 429-37. ISSN 0265-9247 (Print)0265-9247 (Linking)

Abstract

The tropomyosins are a family of actin filament binding proteins. In multicellular animals, they exhibit extensive cell type specific isoform diversity. In this essay we discuss the genetic mechanisms by which this diversity is generated and its possible significance to cellular function.

Item Type: Paper
Uncontrolled Keywords: Amino Acid Sequence Animal Population Groups/genetics Animals Brain Chemistry Cells, Cultured Fibroblasts/metabolism Fungi/genetics Gene Expression Regulation Genes Genes, Fungal Molecular Sequence Data *Multigene Family Muscle Proteins/analysis Nerve Tissue Proteins/analysis Organ Specificity Sequence Homology, Nucleic Acid Species Specificity Tropomyosin/classification/*genetics
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > gene expression
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > myosin
CSHL Authors:
Communities: CSHL labs > Helfman lab
Depositing User: Matt Covey
Date: September 1991
Date Deposited: 21 Dec 2015 22:00
Last Modified: 21 Dec 2015 22:00
Related URLs:
URI: https://repository.cshl.edu/id/eprint/32112

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