Ca2+ signaling in dendritic spines

Sabatini, B. L., Maravall, M., Svoboda, K. (June 2001) Ca2+ signaling in dendritic spines. Current Opinion in Neurobiology, 11 (3). pp. 349-356. ISSN 0959-4388

URL: http://www.ncbi.nlm.nih.gov/pubmed/11399434

DOI: 10.1016/S0959-4388(00)00218-X

Abstract

Dendritic spines are cellular microcompartments that are isolated from their parent dendrites and neighboring spines. Recently, imaging studies of spine Ca2+ dynamics have revealed that Ca2+ can enter spines through voltage-sensitive and ligand-activated channels, as well as through Ca2+ release from intracellular stores. Relationships between spine Ca2+ signals and induction of various forms of synaptic plasticity are beginning to be elucidated. Measurements of spine Ca2+ concentration are also being used to probe the properties of single synapses and even individual calcium channels in their native environment.

Item Type:	Paper
Uncontrolled Keywords:	PROPAGATING ACTION-POTENTIALS HIPPOCAMPAL-NEURONS CALCIUM DYNAMICS SINGLE SPINES SYNAPTIC CURRENTS NMDA RECEPTORS PYRAMIDAL NEURONS PURKINJE-CELLS FINE DENDRITES PLASTICITY
Subjects:	organs, tissues, organelles, cell types and functions > sub-cellular tissues: types and functions > calcium channel organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > cell signaling organs, tissues, organelles, cell types and functions > cell types and functions > cell types > dendritic cells > dendritic spines organs, tissues, organelles, cell types and functions > cell types and functions > cell types > dendritic cells > dendritic spines organs, tissues, organelles, cell types and functions > cell types and functions > cell types > dendritic cells > dendritic spines organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > pyramidal neurons organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > pyramidal neurons organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > pyramidal neurons
CSHL Authors:	Maravall, Miguel Sabatini, Bernardo L. Svoboda, Karel
Communities:	CSHL labs > Svoboda lab
Depositing User:	Matt Covey
Date:	June 2001
Date Deposited:	17 Jan 2014 14:56
Last Modified:	17 Jan 2014 14:56
Related URLs:	Publisher
URI:	https://repository.cshl.edu/id/eprint/29291

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