Tolia, N. H., Joshua-Tor, L. (January 2007) Slicer and the Argonautes. Nature Chemical Biology, 3 (1). pp. 36-43. ISSN 1552-4450
DOI: 10.1038/nchembio848
Abstract
Though they started out as somewhat mysterious components of the RNAi effector complexes, Argonaute proteins have since taken center stage in RNAi gene silencing. They interact with small RNAs to effect gene silencing in all RNAi-related pathways known so far. We will review the dramatic advances in our understanding of the role of the Argonautes in RNAi through studies of their structure and function.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | INDUCED SILENCING COMPLEX RNAI EFFECTOR COMPLEXES C-ELEGANS CRYSTAL-STRUCTURE MESSENGER-RNA PAZ DOMAIN SCHIZOSACCHAROMYCES-POMBE HETEROCHROMATIN FORMATION PASSENGER-STRAND UBIQUITIN LIGASE |
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > RNAi bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > argonaute proteins bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > sRNA |
| CSHL Authors: | |
| Communities: | CSHL labs > Joshua-Tor lab School of Biological Sciences > Publications |
| Depositing User: | CSHL Librarian |
| Date: | January 2007 |
| Date Deposited: | 03 Nov 2011 14:40 |
| Last Modified: | 26 Sep 2014 14:21 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/23156 |
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