Items where Subject is "Ras"

Paper

Bar-Sagi, D. (April 1992) Mechanisms of signal transduction by Ras. Semin Cell Biol, 3 (2). pp. 93-8. ISSN 1043-4682 (Print)1043-4682 (Linking)

Bar-Sagi, D. (May 1994) The Sos (Son of Sevenless) Protein. Trends in Endocrinology and Metabolism, 5 (4). pp. 165-169. ISSN 1043-2760

Bar-Sagi, D., Gomperts, B. D. (October 1988) Stimulation of exocytotic degranulation by microinjection of the ras oncogene protein into rat mast cells. Oncogene, 3 (4). pp. 463-9. ISSN 0950-9232

Bar-Sagi, D., Suhan, J. P., McCormick, F., Feramisco, J. R. (May 1988) Localization of phospholipase A2 in normal and ras-transformed cells. J Cell Biol, 106 (5). pp. 1649-58. ISSN 0021-9525

Beranger, F., Paterson, H., Powers, S., de Gunzburg, J., Hancock, J. F. (January 1994) The effector domain of Rab6, plus a highly hydrophobic C terminus, is required for Golgi apparatus localization. Mol Cell Biol, 14 (1). pp. 744-58. ISSN 0270-7306 (Print)0270-7306

Bhattacharya, S., Chen, L., Broach, J. R., Powers, S. (March 1995) Ras membrane targeting is essential for glucose signaling but not for viability in yeast. Proceedings of the National Academy of Sciences of the United States of America, 92 (7). pp. 2984-8. ISSN 0027-8424

Boettner, B., Govek, E., Van Aelst, L. (November 1998) AF6: A binding partner and putative effector of Ras oncoproteins. Molecular Biology of the Cell, 9. 462A-462A. ISSN 1059-1524

Boettner, B., Govek, E. E., Cross, J., Van Aelst, L. (August 2000) The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proceedings of the National Academy of Sciences of the United States of America, 97 (16). pp. 9064-9069. ISSN 0027-8424

Boettner, B., Van Aelst, L. (August 2002) The RASputin effect. Genes & Development, 16 (16). pp. 2033-2038. ISSN 0890-9369

Boyer, M. J., Gutmann, D. H., Collins, F. S., Bar-Sagi, D. (February 1994) Crosslinking of the surface immunoglobulin receptor in B lymphocytes induces a redistribution of neurofibromin but not p120-GAP. Oncogene, 9 (2). pp. 349-57. ISSN 0950-9232 (Print)

Catanzaro, J. M., Sheshadri, N., Pan, J. A., Sun, Y., Shi, C., Li, J., Powers, R. S., Crawford, H. C., Zong, W. X. (April 2014) Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4. Nature Communications, 5. p. 3729. ISSN 20411723

Chen, L., Powers, S. (1995) RAS in yeast: complementation assays for test of function. Methods in Enzymology, 255. pp. 465-8. ISSN 00766879 (ISSN)

Chen, L., Powers, S. (September 1994) A mutation in the effector region of Ras2 can be partially suppressed by alteration of a 'nonessential' region of Ras. Gene, 147 (1). pp. 107-10. ISSN 0378-1119 (Print)0378-1119

Chen, R. A., Michaeli, T., Van Aelst, L., Ballester, R. (April 2000) A role for the noncatalytic N terminus in the function of Cdc25, a Saccharomyces cerevisiae Ras-guanine nucleotide exchange factor. Genetics, 154 (4). pp. 1473-1484. ISSN 0016-6731

Chen, S. Y., Huff, S. Y., Lai, C. C., Der, C. J., Powers, S. (September 1994) Ras-15A protein shares highly similar dominant-negative biological properties with Ras-17N and forms a stable, guanine-nucleotide resistant complex with CDC25 exchange factor. Oncogene, 9 (9). pp. 2691-8. ISSN 0950-9232 (Print)0950-9232

Cheng, Derek K, Oni, Tobiloba E, Thalappillil, Jennifer S, Park, Youngkyu, Ting, Hsiu-Chi, Alagesan, Brinda, Prasad, Nadia V, Addison, Kenneth, Rivera, Keith D, Pappin, Darryl J, Van Aelst, Linda, Tuveson, David A (May 2021) Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer. Proceedings of the National Academy of Sciences of USA, 118 (21). e2016904118-e2016904118. ISSN 0027-8424

Cockcroft, S., Bar-Sagi, D. (1990) Effect of H-ras proteins on the activity of polyphosphoinositide phospholipase C in HL60 membranes. Cell Signal, 2 (3). pp. 227-34. ISSN 0898-6568 (Print)0898-6568 (Linking)

Connell, L. E., Helfman, D. M. (November 2001) Role of actin and myosin in apoptosis in normal and Ras-transformed MDCK cells. Molecular Biology of the Cell, 12. 194A-195A. ISSN 1059-1524

Corbo, V., Ponz-Sarvise, M., Tuveson, D. A. (September 2014) The RAS and YAP1 dance, who is leading? EMBO journal, 33 (21). pp. 3437-2438. ISSN 0261-4189

Dent, P., Booth, L., Roberts, J. L., Liu, J., Poklepovic, A., Lalani, A. S., Tuveson, D., Martinez, J., Hancock, J. F. (June 2019) Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells. Oncogene. ISSN 0950-9232

Di Cristofano, A., Niki, M., Zhao, M. M., Karnell, F. G., Clarkson, B., Pear, W. S., Van Aelst, L., Pandolfi, P. P. (August 2001) p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl). Journal of Experimental Medicine, 194 (3). pp. 275-284. ISSN 0022-1007

Fagegaltier, D., Falciatori, I., Czech, B., Castel, S., Perrimon, N., Simcox, A., Hannon, G. J. (July 2016) Oncogenic transformation of Drosophila somatic cells induces a functional piRNA pathway. Genes Dev, 30 (14). pp. 1623-35. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Ferbeyre, G., de Stanchina, E., Querido, E., Baptiste, N., Prives, C., Lowe, S. W. (August 2000) PML is induced by oncogenic ras and promotes premature senescence. Genes & Development, 14 (16). pp. 2015-2027. ISSN 0890-9369

Field, J., Colicelli, J., Vojtek, A., Ballester, R., Ferguson, K., Chester, N., Michaeli, T., Gerst, J., Riggs, M. (1990) Ras from the Yeast Perspective. Journal of Cellular Biochemistry, 44 (S14C). p. 124.

Gale, N. W., Graziadel, L. S., Bar-Sagi, D. (1991) P21-Ras Involvement in T-Lymphocyte Activation. Journal of Cellular Biochemistry, 47 (Suppl ). p. 137.

Gale, N. W., Kaplan, S., Lowenstein, E. J., Schlessinger, J., Bar-Sagi, D. (May 1993) Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras. Nature, 363 (6424). pp. 88-92. ISSN 0028-0836 (Print)

Giese, K. P., Friedman, E., Telliez, J. B., Fedorov, N. B., Wines, M., Feig, L. A., Silva, A. J. (November 2001) Hippocampus-dependent learning and memory is impaired in mice lacking the Ras-guanine-nucleotide releasing factor 1 (Ras-GRF1). Neuropharmacology, 41 (6). pp. 791-800. ISSN 0028-3908

Goodman, L. E., Judd, S. R., Farnsworth, C. C., Powers, S., Gelb, M. H., Glomset, J. A., Tamanoi, F. (December 1990) Mutants of Saccharomyces cerevisiae defective in the farnesylation of Ras proteins. Proceedings of the National Academy of Sciences of the United States of America, 87 (24). pp. 9665-9. ISSN 0027-8424 (Print)0027-8424

Graziadei, L., Riabowol, K., Bar-Sagi, D. (September 1990) Co-capping of ras proteins with surface immunoglobulins in B lymphocytes. Nature, 347 (6291). pp. 396-400. ISSN 0028-0836 (Print)0028-0836 (Linking)

Hart, M., Powers, S. (1995) Ras-Cdc25 and Rho-Dbl binding assays: complex formation in vitro. Methods in Enzymology, 255. pp. 129-35. ISSN 00766879 (ISSN)

He, B., Chen, P., Chen, S. Y., Vancura, K. L., Michaelis, S., Powers, S. (December 1991) RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins. Proceedings of the National Academy of Sciences of the United States of America, 88 (24). pp. 11373-7. ISSN 0027-8424

Kaplan, S., Bar-Sagi, D. (October 1991) Association of p21ras with cellular polypeptides. J Biol Chem, 266 (28). pp. 18934-41. ISSN 0021-9258 (Print)0021-9258 (Linking)

Kashige, N., Carpino, N., Kobayashi, R. (February 2000) Tyrosine phosphorylation of p62(dok) by p210(bcr-abl) inhibits RasGAP activity. Proceedings of the National Academy of Sciences of the United States of America, 97 (5). pp. 2093-2098. ISSN 0027-8424

Kim, J. H., Powers, S. (August 1991) Overexpression of RPI1, a novel inhibitor of the yeast Ras-cyclic AMP pathway, down-regulates normal but not mutationally activated ras function. Molecular and Cellular Biology, 11 (8). pp. 3894-904. ISSN 0270-7306

Kumar, C. C., Chang, C. (January 1992) Human Smooth-Muscle Myosin Light Chain-2 Gene Expression Is Repressed in Ras Transformed Fibroblast Cells. Cell Growth & Differentiation, 3 (1). pp. 1-10. ISSN 1044-9523

Lai, C. C., Boguski, M., Broek, D., Powers, S. (March 1993) Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins. Mol Cell Biol, 13 (3). pp. 1345-52. ISSN 0270-7306 (Print)0270-7306

Lee, C. S., Lee, L. C., Yuan, T. L., Chakka, S., Fellmann, C., Lowe, S. W., Caplen, N. J., McCormick, F., Luo, J. (February 2019) MAP kinase and autophagy pathways cooperate to maintain RAS mutant cancer cell survival. Proc Natl Acad Sci U S A, 116 (10). pp. 4508-4517. ISSN 0027-8424

Lee, S., Helfman, D. M. (November 2001) Regulation of caldesmon expression and function in normal and Ras-transformed fibroblasts. Molecular Biology of the Cell, 12. 51A-51A. ISSN 1059-1524

Li, N., Batzer, A., Daly, R., Yajnik, V., Skolnik, E., Chardin, P., Bar-Sagi, D., Margolis, B., Schlessinger, J. (May 1993) Guanine-Nucleotide-Releasing Factor Hsos1 Binds to Grb2 and Links Receptor Tyrosine Kinases to Ras Signaling. Nature, 363 (6424). pp. 85-88. ISSN 0028-0836

Lin, A. W., Lowe, S. W. (April 2001) Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation. Proceedings of the National Academy of Sciences of the United States of America, 98 (9). pp. 5025-5030. ISSN 0027-8424

Lowe, S. W. (March 1999) Activation of p53 by oncogenes. Endocr Relat Cancer, 6 (1). pp. 45-8. ISSN 1351-0088 (Print)

Lowenstein, E. J., Daly, R. J., Batzer, A. G., Li, W., Margolis, B., Lammers, R., Ullrich, A., Skolnik, E. Y., Bar-Sagi, D., Schlessinger, J. (August 1992) The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling. Cell, 70 (3). pp. 431-42. ISSN 0092-8674 (Print)0092-8674 (Linking)

Luo, Y., Yang, Y., Liu, M., Wang, D., Wang, F., Bi, Y., Ji, J., Li, S., Liu, Y., Chen, R., Huang, H., Wang, X., Swidnicka-Siergiejko, A. K., Janowitz, T., Beyaz, S., Wang, G., Xu, S., Bialkowska, A. B., Luo, C. K., Pin, C. L., Liang, G., Lu, X., Wu, M., Shroyer, K. R., Wolff, R. A., Plunkett, W., Ji, B., Li, Z., Li, E., Li, X., Yang, V. W., Logsdon, C. D., Abbruzzese, J. L., Lu, W. (July 2019) Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet. Gastroenterology, 157 (5). ISSN 0016-5085

Mathew, G., Hannan, A., Hertzler-Schaefer, K., Wang, F., Feng, G. S., Zhong, J., Zhao, J. J., Downward, J., Zhang, X. (November 2016) Targeting of Ras-mediated FGF signaling suppresses Pten-deficient skin tumor. Proc Natl Acad Sci U S A, 113 (46). pp. 13156-13161. ISSN 1091-6490 (Electronic)0027-8424 (Linking)

Neuwald, A. F., Kannan, N., Poleksic, A., Hata, N., Liu, J. S. (April 2003) Ran's C-terminal, basic patch, and nucleotide exchange mechanisms in light of a canonical structure for Rab, Rho, Ras, and Ran GTPases. Genome Research, 13 (4). pp. 673-692. ISSN 1088-9051

Powers, S. (August 1992) Genetic analysis of ras homologs in yeasts. Semin Cancer Biol, 3 (4). pp. 209-18. ISSN 1044-579X (Print)1044-579x

Powers, S., Gonzales, E., Christensen, T., Cubert, J., Broek, D. (June 1991) Functional cloning of BUD5, a CDC25-related gene from S. cerevisiae that can suppress a dominant-negative RAS2 mutant. Cell, 65 (7). pp. 1225-31. ISSN 0092-8674 (Print)0092-8674

Ruggieri, R., Bender, A., Matsui, Y., Powers, S., Takai, Y., Pringle, J. R., Matsumoto, K. (February 1992) RSR1, a ras-like gene homologous to Krev-1 (smg21A/rap1A): role in the development of cell polarity and interactions with the Ras pathway in Saccharomyces cerevisiae. Molecular and Cellular Biology, 12 (2). pp. 758-66. ISSN 0270-7306

Schneider, B. L., Bowden, G. T., Sutter, C., Schweizer, J., Han, K. A., Kuleszmartin, M. F. (October 1993) 7,12-Dimethylbenz[a]Anthracene-Induced Mouse Keratinocyte Malignant Transformation Independent of Harvey Ras Activation. Journal of Investigative Dermatology, 101 (4). pp. 595-599. ISSN 0022-202X

Serrano, M., Lin, A. W., McCurrach, M. E., Beach, D., Lowe, S. W. (March 1997) Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell, 88 (5). pp. 593-602. ISSN 0092-8674 (Print)

Shields, J. M., Der, C. J., Powers, S. (2001) Identification of Ras-regulated genes by representational difference analysis. Methods in Enzymology, 332. pp. 221-32. ISSN 00766879 (ISSN)

Sun, H., Tonks, N. K., Barsagi, D. (October 1994) Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1. Science, 266 (5183). pp. 285-288. ISSN 0036-8075

Thorburn, A., Thorburn, J., Chen, S. Y., Powers, S., Shubeita, H. E., Feramisco, J. R., Chien, K. R. (January 1993) HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy. Journal of Biological Chemistry, 268 (3). pp. 2244-9. ISSN 0021-9258

Tokiwa, G., Tyers, M., Volpe, T., Futcher, B. (September 1994) Inhibition of G1 cyclin activity by the Ras/cAMP pathway in yeast. Nature, 371 (6495). pp. 342-5. ISSN 0028-0836 (Print)

Van Aelst, L., D'Souza-Schorey, C. (September 1997) Rho GTPases and signaling networks. Genes and Development, 11 (18). pp. 2295-322. ISSN 08909369 (ISSN)

Yang, M., Haase, A. D., Huang, F. K., Coulis, G., Rivera, K. D., Dickinson, B. C., Chang, C. J., Pappin, D. J., Neubert, T. A., Hannon, G. J., Boivin, B., Tonks, N. K. (August 2014) Dephosphorylation of Tyrosine 393 in Argonaute 2 by Protein Tyrosine Phosphatase 1B Regulates Gene Silencing in Oncogenic RAS-Induced Senescence. Mol Cell, 55 (5). pp. 782-790. ISSN 1097-2765

Yart, A., Laffargue, M., Mayeux, P., Chretien, S., Peres, C., Tonks, N., Roche, S., Payrastre, B., Chap, H., Raynal, P. (March 2001) A critical pole for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of Ras and mitogen-activated protein kinases by epidermal growth factor. Journal of Biological Chemistry, 276 (12). pp. 8856-8864. ISSN 0021-9258

Zhao, Z., Chen, C. C., Rillahan, C. D., Shen, R., Kitzing, T., McNerney, M. E., Diaz-Flores, E., Zuber, J., Shannon, K., Le Beau, M. M., Spector, M. S., Kogan, S. C., Lowe, S. W. (March 2015) Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis. Nature Genetics, 47. pp. 539-543. ISSN 1061-4036

Zhu, J. J., Qin, Y., Zhao, M. M., Van Aelst, L., Malinow, R. (August 2002) Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell, 110 (4). pp. 443-455. ISSN 0092-8674

Book Section

Bar-Sagi, D. (1989) Phospholipase a-2 in Ras-Transformed Cells. In: Cell activation and signal initiation : receptor and phospholipase control of inositol phosphate, PAF, and eicosanoid production : proceedings of a UCLA symposium held in Keystone, Colorado, April 17-23, 1988. Ucla (University of California-Los Angeles) Symposia on Molecular and Cellular Biology New Series, 106 (ED.). Alan R. Liss, Inc., New York, pp. 331-336. ISBN 0845147056

Boettner, B., Herrmann, C., Van Aelst, L. (2001) Ras and Rap1 interaction with AF-6 effector target. In: Regulators and Effectors of Small Gtpases, Pt F, Ras Family I. Methods of Enzymology, 332 . Elsevier, pp. 151-168. ISBN 0076-6879

Powers, S., Michaelis, S. (1988) Biogenesis of yeast mating pheromone a-factor and Ras proteins. In: Molecular biology of intracellular protein sorting and organelle assembly: proceedings of a DuPont-UCLA symposium held in Taos, New Mexico, January 30-February 5, 1987. Liss. ISBN 9780845126752

Video

Van Aelst, L. (November 2011) Talk from Linda Van Aelst at the Cold Spring Harbor Laboratory In-House Symposium (2011). [Video] (Unpublished)