Items where Subject is "Akt"

Paper

Crompton, J. G., Sukumar, M., Roychoudhuri, R., Clever, D., Gros, A., Eil, R. L., Tran, E., Hanada, K., Yu, Z., Palmer, D. C., Kerkar, S. P., Michalek, R. D., Upham, T., Leonardi, A., Acquavella, N., Wang, E., Marincola, F. M., Gattinoni, L., Muranski, P., Sundrud, M. S., Klebanoff, C. A., Rosenberg, S. A., Fearon, D. T., Restifo, N. P. (January 2015) Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics. Cancer Res, 75 (2). pp. 296-305. ISSN 0008-5472

Hernando, E., Charytonowicz, E., Dudas, M. E., Menendez, S., Matushansky, I., Mills, J., Socci, N. D., Behrendt, N., Ma, L., Maki, R. G., Pandolfi, P. P., Cordon-Cardo, C. (June 2007) The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas. Nat Med, 13 (6). pp. 748-53. ISSN 1078-8956 (Print)1078-8956 (Linking)

Murray, S. A., Zheng, H. W., Gu, L., Xiao, Z. X. J. (March 2003) IGF-1 activates p21 to inhibit UV-induced cell death. Oncogene, 22 (11). pp. 1703-1711. ISSN 0950-9232

Newton, A. C., Trotman, L. C. (2014) Turning off AKT: PHLPP as a drug target. Annu Rev Pharmacol Toxicol, 54. pp. 537-58. ISSN 1545-4304 (Electronic)0362-1642 (Linking)

Nowak, D. G., Cho, H., Herzka, T., Wang, V. M. Y., Senturk, S., DeMarco, D. V., Ding, D., Fellmann, C., Beinortas, T., Kleinman, D., Watrud, K., Chen, M., Wilkinson, J. E., Castillo-Martin, M., Cordon-Cardo, C., Robinson, B. D., Trotman, L. C. (August 2015) Myc drives Pten/ p53-deficient proliferation and metastasis due to Il6-secretion and Akt-suppression via Phlpp2. Cancer Research, 75 (Supple). Abstract 2258. ISSN 0008-5472

Paik, J. H., Ding, Z. H., Narurkar, R., Ramkissoon, S., Muller, F., Kamoun, W. S., Chae, S. S., Zheng, H. W., Ying, H. Q., Mahoney, J., Hiller, D., Jiang, S., Protopopov, A., Wong, W. H., Chin, L., Ligon, K. L., DePinho, R. A. (November 2009) FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis. Cell Stem Cell, 5 (5). pp. 540-553. ISSN 1934-5909

Perna, D., Karreth, F. A., Rust, A. G., Perez-Mancera, P. A., Rashid, M., Iorio, F., Alifrangis, C., Arends, M. J., Bosenberg, M. W., Bollag, G., Tuveson, D. A., Adams, D. J. (January 2015) BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model. Proceedings of the National Academy of Sciences of the United States of America, 112 (6). E536-E545. ISSN 0027-8424

Ponz-Sarvise, M., Corbo, V., Tiriac, H., Engle, D. D., Frese, K. K., Oni, T. E., Hwang, C. I., Ohlund, D., Chio, I. I. C., Baker, L. A., Filippini, D., Wright, K., Bapiro, T. E., Huang, P. S., Smith, P. D., Yu, K. H., Jodrell, D. I., Park, Y., Tuveson, D. A. (September 2019) Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer. Clin Cancer Res, 25 (22). pp. 6742-6755. ISSN 1078-0432 (Print)1078-0432

Stahlhut, C. E., Watrud, K. E., Ambrico, A. J., Cho, H., Wang, L. L., Qi, J., Cantley, L. C., Bradner, J., Trotman, L. C. (August 2015) Myc vs. Akt therapy in RapidCap, a GEM model for metastatic prostate cancer. Cancer Research, 75 (Supple). Abstract 2636. ISSN 0008-5472

Trotman, L. C., Nowak, D. G., Cho, H., Herzka, T., Watrud, K., DeMarco, D. V., Wang, V. M., Senturk, S., Fellmann, C., Ding, D., Beinortas, T., Kleinman, D., Chen, M., Sordella, R., Wilkinson, J. E., Castillo-Martin, M., Cordon-Cardo, C., Robinson, B. D. (June 2015) Myc drives Pten/trp53-deficient proliferation and metastasis due to Il6-secretion and Akt-suppression via Phlpp2. Cancer Discovery, 5 (6). pp. 636-651. ISSN 21598274

Wendel, H. G., Malina, A., Zhao, Z., Zender, L., Kogan, S. C., Cordon-Cardo, C., Pelletier, J., Lowe, S. W. (August 2006) Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo. Cancer Res, 66 (15). pp. 7639-46. ISSN 0008-5472 (Print)