Items where Community is "CSHL labs > Furukawa lab"

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Paper

Romero-Hernandez, A., Furukawa, H. (2017) Novel mode of antagonist binding in NMDA receptors revealed by the crystal structure of the GluN1-GluN2A ligand-binding domain complexed to NVP-AAM077. Mol Pharmacol, 92 (1). pp. 22-29. ISSN 0026-895x

Amin, J. B., Salussolia, C. L., Chan, K., Regan, M. C., Dai, J., Zhou, H. X., Furukawa, H., Bowen, M. E., Wollmuth, L. P. (2017) Divergent roles of a peripheral transmembrane segment in AMPA and NMDA receptors. J Gen Physiol, 149 (6). pp. 661-680. ISSN 0022-1295

Romero-Hernandez, Annabel, Simorowski, Noriko, Karakas, Erkan, Furukawa, Hiro (2016) Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain. Neuron, 92 (6). pp. 1324-1336. ISSN 0896-6273

Regan, Michael C., Furukawa, Hiro (2016) Deeper Insights into the Allosteric Modulation of Ionotropic Glutamate Receptors. Neuron, 91 (6). pp. 1187-1189. ISSN 0896-6273

Malinauskas, Tomas, Furukawa, Hiro (2016) Production of Heteromeric Transmembrane Receptors with Defined Subunit Stoichiometry. Structure, 24 (5). pp. 653-655. ISSN 0969-2126

Tajima, N., Karakas, E., Grant, T., Simorowski, N., Diaz-Avalos, R., Grigorieff, N., Furukawa, H. (2016) Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Nature, 534 (7605). pp. 63-8. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Cai, Na, Li, Yihan, Chang, Simon, Liang, Jieqin, Lin, Chongyun, Zhang, Xiufei, Liang, Lu, Hu, Jingchu, Chan, Wharton, Kendler, Kenneth S, Malinauskas, Tomas, Huang, Guo-Jen, Li, Qibin, Mott, Richard, Flint, Jonathan (2015) Genetic Control over mtDNA and Its Relationship to Major Depressive Disorder. Current Biology, 25 (24). pp. 3170-3177. ISSN 0960-9822

Regan, Michael C., Romero-Hernandez, Annabel, Furukawa, Hiro (2015) A structural biology perspective on NMDA receptor pharmacology and function. Current Opinion in Structural Biology, 33. pp. 68-75. ISSN 0959-440X

van Schouwenburg, Pauline A., Davenport, Emma E., Kienzler, Anne-Kathrin, Marwah, Ishita, Wright, Benjamin, Lucas, Mary, Malinauskas, Tomas, Martin, Hilary C., Lockstone, Helen E., Cazier, Jean-Baptiste, Chapel, Helen M., Knight, Julian C., Patel, Smita Y. (2015) Application of whole genome and RNA sequencing to investigate the genomic landscape of common variable immunodeficiency. Clinical Immunology, 160 (2). pp. 301-314. ISSN 1521-6616

Karakas, Erkan, Regan, Michael C., Furukawa, Hiro (2015) Emerging structural insights into the function of ionotropic glutamate receptors. Trends in Biochemical Sciences, 40 (6). pp. 328-337. ISSN 0968-0004

Bauza, K., Atcheson, E., Malinauskas, T., Blagborough, A. M., Reyes-Sandoval, A. (2015) Tailoring a Combination Preerythrocytic Malaria Vaccine. Infect Immun, 84 (3). pp. 622-34. ISSN 1098-5522 (Electronic)0019-9567 (Linking)

Malinauskas, Tomas, Jones, E. Yvonne (2014) Extracellular modulators of Wnt signalling. Current Opinion in Structural Biology, 29. pp. 77-84. ISSN 0959-440X

Khatri, A., Burger, P. B., Swanger, S. A., Hansen, K. B., Zimmerman, S., Karakas, E., Liotta, D. C., Furukawa, H., Snyder, J. P., Traynelis, S. F. (2014) Structural Determinants and Mechanism of Action of a GluN2C-selective NMDA Receptor Positive Allosteric Modulator. Mol Pharmacol, 86 (5). pp. 548-560. ISSN 0026-895x

Karakas, E., Furukawa, H. (2014) Crystal structure of a heterotetrameric NMDA receptor ion channel. Science, 344 (6187). pp. 992-7. ISSN 1095-9203 (Electronic)0036-8075 (Linking)

Jespersen, A., Tajima, N., Fernandez-Cuervo, G., Garnier-Amblard, E. C., Furukawa, H. (2014) Structural Insights into Competitive Antagonism in NMDA Receptors. Neuron, 81 (2). pp. 366-78. ISSN 0896-6273

Hansen, K. B., Tajima, N., Risgaard, R., Perszyk, R. E., Jorgensen, L., Vance, K. M., Ogden, K. K., Clausen, R. P., Furukawa, H., Traynelis, S. F. (2013) Structural determinants of agonist efficacy at the glutamate binding site of n-methyl-d-Aspartate receptorss. Molecular Pharmacology, 84 (1). pp. 114-127. ISSN 0026895X

Salussolia, C. L., Gan, Q., Kazi, R., Singh, P., Allopenna, J., Furukawa, H., Wollmuth, L. P. (2013) A eukaryotic specific transmembrane segment is required for tetramerization in AMPA receptors. Journal of Neuroscience, 33 (23). pp. 9840-9845. ISSN 02706474

Burger, P. B., Yuan, H. J., Karakas, E., Geballe, M., Furukawa, H., Liotta, D. C., Snyder, J. P., Traynelis, S. F. (2012) Mapping the Binding of GluN2B-Selective N-Methyl-D-aspartate Receptor Negative Allosteric Modulators. Molecular Pharmacology, 82 (2). pp. 344-359. ISSN 0026-895X

Furukawa, H. (2012) Structure and function of glutamate receptor amino terminal domains. Journal of Physiology, 590 (1). pp. 63-72. ISSN 00223751 (ISSN)

Karakas, E., Simorowski, N., Furukawa, H. (2011) Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors. Nature, 475 (7355). 249- U170. ISSN 00280836

Vance, K. M., Simorowski, N., Traynelis, S. F., Furukawa, H. (2011) Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors. Nature Communications, 2. ISSN 2041-1723

Hansen, K. B., Furukawa, H., Traynelis, S. F. (2010) Control of Assembly and Function of Glutamate Receptors by the Amino-Terminal Domain. Molecular Pharmacology, 78 (4). pp. 535-549. ISSN 0026-895X

Karakas, Erkan, Simorowski, Noriko, Furukawa, Hiro (2010) Structural Insights into Allosteric Modulation of NMDA Receptors Through the Amino-Terminal Domain. Biophysical Journal, 98 (3, Sup). 609a-609a.

Karakas, E., Simorowski, N., Furukawa, H. (2009) Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit. Embo Journal, 28 (24). pp. 3910-3920. ISSN 0261-4189

Jin, R., Singh, S. K., Gu, S., Furukawa, H., Sobolevsky, A. I., Zhou, J., Jin, Y., Gouaux, E. (2009) Crystal structure and association behaviour of the GluR2 amino-terminal domain. Embo J, 28 (12). pp. 1812-23. ISSN 1460-2075 (Electronic)1460-2075 (Linking)

Jasti, J., Furukawa, H., Gonzales, E. B., Gouaux, E. (2007) Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH. Nature, 449 (7160). pp. 316-23. ISSN 1476-4687 (Electronic) 1476-4687 (Linking)

Vasquez, V., Cortes, D. M., Furukawa, H., Perozo, E. (2007) An optimized purification and reconstitution method for the MscS channel: strategies for spectroscopical analysis. Biochemistry, 46 (23). pp. 6766-73. ISSN 0006-2960 (Print)0006-2960 (Linking)

Takahashi, H., Shin, Y., Cho, S. J., Zago, W. M., Nakamura, T., Gu, Z., Ma, Y., Furukawa, H., Liddington, R., Zhang, D., Tong, G., Chen, H. S., Lipton, S. A. (2007) Hypoxia enhances S-nitrosylation-mediated NMDA receptor inhibition via a thiol oxygen sensor motif. Neuron, 53 (1). pp. 53-64. ISSN 0896-6273 (Print)0896-6273 (Linking)

Furukawa, H., Singh, S. K., Mancusso, R., Gouaux, E. (2005) Subunit arrangement and function in NMDA receptors. Nature, 438 (7065). pp. 185-192. ISSN 0028-08361476-4687 (Electronic)1476-4687 (Linking)

Inanobe, A., Furukawa, H., Gouaux, E. (2005) Mechanism of partial agonist action at the NR1 subunit of NMDA receptors. Neuron, 47 (1). pp. 71-84. ISSN 0896-6273 (Print)0896-6273 (Linking)

Furukawa, H., Gouaux, E. (2003) Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core. Embo J, 22 (12). pp. 2873-85. ISSN 0261-4189 (Print)0261-4189 (Linking)

Furukawa, H., Hamada, T., Hayashi, M. K., Haga, T., Muto, Y., Hirota, H., Yokoyama, S., Nagasawa, K., Ishiguro, M. (2002) Conformation of ligands bound to the muscarinic acetylcholine receptor. Mol Pharmacol, 62 (4). pp. 778-87. ISSN 0026-895X (Print)0026-895X (Linking)

Furukawa, H., Haga, T. (2000) Expression of functional M2 muscarinic acetylcholine receptor in Escherichia coli. J Biochem, 127 (1). pp. 151-61. ISSN 0021-924X (Print)

Book Section

Furukawa, H, Hamada, T, Ishiguro, M, Hirota, H, Haga, T (2005) Determination of steric structure of muscarinic ligands bound to muscarinic receptors: approaches by TRNOE (transferred nuclear Overhauser effect). In: G protein-coupled receptors: structure, function, and ligand screening. CRC Press, pp. 261-281. ISBN 978-0-8493-2771-1

Patent

Hiro Furukawa (2014) Phenylethanolamine-based NMDA receptor antagonists. United States Patent 8648198. .

Video

Furukawa, H. (2011) Talk from Hiro Furukawa at the Cold Spring Harbor Laboratory In-House Symposium (2011). [Video] (Unpublished)

This list was generated on Wed Jul 26 02:57:39 2017 EDT.
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