Sheltzer, Jason Publications

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Sheltzer, Jason

Number of items at this level: 19.

Paper

Lin, A., Giuliano, C. J., Palladino, A., John, K. M., Abramowicz, C., Yuan, M. L., Sausville, E. L., Lukow, D. A., Liu, L., Chait, A. R., Galluzzo, Z. C., Tucker, C., Sheltzer, J. M. (September 2019) Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials. Sci Transl Med, 11 (509). ISSN 1946-6234

Giuliano, C. J., Lin, A., Girish, V., Sheltzer, J. M. (August 2019) Generating Single Cell–Derived Knockout Clones in Mammalian Cells with CRISPR/Cas9. Current Protocols in Molecular Biology, 128 (1). Art number e100. ISSN 19343639 (ISSN)

Smith, J. C., Sheltzer, J. M. (December 2018) Systematic identification of mutations and copy number alterations associated with cancer patient prognosis. Elife, 7. ISSN 2050-084x

Sheltzer, J. M. (October 2018) Gender disparities among independent fellows in biomedical research. Nat Biotechnol, 36 (10). pp. 1018-1021. ISSN 1087-0156

Giuliano, C. J., Lin, A., Smith, J. C., Palladino, A. C., Sheltzer, J. M. (July 2018) Combining CRISPR/Cas9 mutagenesis and a small-molecule inhibitor to probe the function of MELK in cancer. Cancer Research, 78 (13 S). Meeting Abstract: 837A . ISSN 0008-5472

Giuliano, C. J., Lin, A., Smith, J. C., Palladino, A. C., Sheltzer, J. M. (February 2018) MELK expression correlates with tumor mitotic activity but is not required for cancer growth. Elife, 7. ISSN 2050-084x

Lin, A., Giuliano, C. J., Sayles, N. M., Sheltzer, J. M. (March 2017) CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials. Elife, 6. e24179. ISSN 2050-084x

Sheltzer, Jason M., Ko, Julie H., Replogle, John M., Habibe Burgos, Nicole C., Chung, Erica S., Meehl, Colleen M., Sayles, Nicole M., Passerini, Verena, Storchova, Zuzana, Amon, Angelika (February 2017) Single-chromosome Gains Commonly Function as Tumor Suppressors. Cancer Cell, 31 (2). pp. 240-255. ISSN 1535-6108 (Public Dataset)

Sheltzer, J. (December 2016) Single-chromosome aneuploidy commonly functions as a tumor suppressor. Molecular Biology of the Cell, 27. A10. ISSN 1059-1524

Dodgson, S. E., Santaguida, S., Kim, S., Sheltzer, J., Amon, A. (November 2016) The pleiotropic deubiquitinase Ubp3 confers aneuploidy tolerance. Genes Dev. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Blank, H. M., Sheltzer, J. M., Meehl, C. M., Amon, A. (April 2015) Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast. Mol Biol Cell, 26 (8). pp. 1440-51. ISSN 1939-4586 (Electronic)1059-1524 (Linking)

McGregor, J (July 2014) Study: Top labs run by men tend to hire fewer women. Washington Post.

Sheltzer, J. M., Smith, J. C. (July 2014) Elite male faculty in the life sciences employ fewer women. Proc Natl Acad Sci U S A, 111 (28). pp. 10107-12. ISSN 1091-6490 (Electronic)0027-8424 (Linking)

Sheltzer, J. M. (November 2013) A transcriptional and metabolic signature of primary aneuploidy is present in chromosomally unstable cancer cells and informs clinical prognosis. Cancer Res, 73 (21). pp. 6401-12. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Sheltzer, J. M., Torres, E. M., Dunham, M. J., Amon, A. (July 2012) Transcriptional consequences of aneuploidy. Proc Natl Acad Sci U S A, 109 (31). pp. 12644-9. ISSN 1091-6490 (Electronic)0027-8424 (Linking)

Sheltzer, J. M., Amon, A. (November 2011) The aneuploidy paradox: costs and benefits of an incorrect karyotype. Trends Genet, 27 (11). pp. 446-53. ISSN 0168-9525 (Print)0168-9525 (Linking)

Sheltzer, J. M., Blank, H. M., Pfau, S. J., Tange, Y., George, B. M., Humpton, T. J., Brito, I. L., Hiraoka, Y., Niwa, O., Amon, A. (August 2011) Aneuploidy drives genomic instability in yeast. Science, 333 (6045). pp. 1026-30. ISSN 1095-9203 (Electronic)0036-8075 (Linking)

Akst, J. (August 2011) Chromosomes and Cancer. The Scientist.

Sheltzer, J. M., Rose, M. D. (June 2009) The class V myosin Myo2p is required for Fus2p transport and actin polarization during the yeast mating response. Mol Biol Cell, 20 (12). pp. 2909-19. ISSN 1939-4586 (Electronic)1059-1524 (Linking)

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