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Paper

Tonelli, Claudia, Deschênes, Astrid, Gaeth, Victoria A, Jensen, Amanda, Vithlani, Nandan, Yao, Melissa A, Zhao, Zhen, Park, Youngkyu, Tuveson, David A (April 2025) FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development. Cancer Research. ISSN 0008-5472 (Public Dataset)

Zhou, Edward, Yang, Jung-In, Habowski, Amber N, Deschênes, Astrid, Belleau, Pascal, Ha, Taehoon, Tzanavaris, Chris J, Boyd, Jeff, Hollweg, Christopher A, Zhu, Xinhua, Tuveson, David A, King, Daniel A (April 2025) GATA6 Amplification Is Associated With Improved Survival in TP53-Mutated Unresectable Pancreatic Cancer. Pancreas, 54 (4). e303-e309. ISSN 1536-4828

Tuveson, David, Tonelli, Claudia, Deschenes, Astrid, Gaeth, Victoria, Jensen, Amanda, Vithlani, Nandan, Yao, Melissa, Zhao, Zhen, Park, Youngkyu (October 2024) Ductal pancreatic cancer interception by FGFR2 abrogation. bioRxiv. ISSN 2692-8205 (Public Dataset) (Submitted)

Tonelli, Claudia, Yordanov, Georgi N, Hao, Yuan, Deschênes, Astrid, Hinds, Juliene, Belleau, Pascal, Klingbeil, Olaf, Brosnan, Erin, Doshi, Abhishek, Park, Youngkyu, Hruban, Ralph H, Vakoc, Christopher R, Dobin, Alexander, Preall, Jonathan, Tuveson, David A (January 2024) A mucus production programme promotes classical pancreatic ductal adenocarcinoma. Gut. ISSN 0017-5749

Belleau, Pascal, Deschênes, Astrid, Chambwe, Nyasha, Tuveson, David A, Krasnitz, Alexander (December 2022) Genetic ancestry inference from cancer-derived molecular data across genomic and transcriptomic platforms. Cancer Research. CAN-22. ISSN 0008-5472

Belleau, Pascal, Deschênes, Astrid, Tuveson, David, Krasnitz, Alexander (February 2022) Accurate and robust inference of genetic ancestry from cancer-derived molecular data across genomic platforms. BioRxiv. (Unpublished)

Tonelli, Claudia, Deschênes, Astrid, Yao, Melissa, Park, Youngkyu, Tuveson, David (January 2022) Loss of p53 tumor suppression function drives invasion and genomic instability in models of murine pancreatic cancer. BioRxiv. (Unpublished)

Maurice, C, Dalvai, M, Lambrot, R, Deschênes, A, Scott-Boyer, MP, McGraw, S, Chan, D, Côté, N, Ziv-Gal, A, Flaws, JA, Droit, A, Trasler, J, Kimmins, S, Bailey, JL (June 2021) Early-life exposure to environmental contaminants perturbs the sperm epigenome and induces negative pregnancy outcomes for three generations via the paternal lineage. Epigenomes, 5 (2). p. 10. ISSN 2075-4655

Oni, T. E., Biffi, G., Baker, L. A., Hao, Y., Tonelli, C., Somerville, T. D. D., Deschênes, A., Belleau, P., Hwang, C. I., Sánchez-Rivera, F. J., Cox, H., Brosnan, E., Doshi, A., Lumia, R. P., Khaledi, K., Park, Y., Trotman, L. C., Lowe, S. W., Krasnitz, A., Vakoc, C. R., Tuveson, D. A. (July 2020) SOAT1 promotes mevalonate pathway dependency in pancreatic cancer. J Exp Med, 217 (9). ISSN 0022-1007

Froeling, F. E. M., Mosur Swamynathan, M., Deschenes, A., Chio, I. I. C., Brosnan, E., Yao, M. A., Alagesan, P., Lucito, M. S., Li, J., Chang, A. Y., Trotman, L. C., Belleau, P., Park, Y., Rogoff, H. A., Watson, J. D., Tuveson, D. A. (September 2019) Bioactivation of napabucasin triggers reactive oxygen species-mediated cancer cell death. Clin Cancer Res, 25 (23). pp. 7162-7174. ISSN 1078-0432 (Print)1078-0432

Tiriac, H., Belleau, P., Engle, D. D., Plenker, D., Deschenes, A., Somerville, T., Froeling, F. E. M., Burkhart, R. A., Denroche, R. E., Jang, G. H., Miyabayashi, K., Young, C. M., Patel, H., Ma, M., LaComb, J. F., Palmaira, R. L. D., Javed, A. A., Huynh, J. A., Johnson, M., Arora, K., Robine, N., Shah, M., Sanghvi, R., Goetz, A. B., Lowder, C. Y., Martello, L., Driehuis, E., Lecomte, N., Askan, G., Iacobuzio-Donahue, C. A., Clevers, H., Wood, L. D., Hruban, R. H., Thompson, E. D., Aguirre, A. J., Wolpin, B. M., Sasson, A., Kim, J., Wu, M., Bucobo, J. C., Allen, P. J., Sejpal, D. V., Nealon, W., Sullivan, J. D., Winter, J. M., Gimotty, P. A., Grem, J. L., DiMaio, D. J., Buscaglia, J. M., Grandgenett, P. M., Brody, J. R., Hollingsworth, M. A., O'Kane, G. M., Notta, F., Kim, E. J., Crawford, J. M., Devoe, C. E., Ocean, A., Wolfgang, C. L., Yu, K. H., Li, E., Vakoc, C. R., Hubert, B., Fischer, S. E., Wilson, J. M., Moffitt, R. A., Knox, J. J., Krasnitz, A., Gallinger, S., Tuveson, D. A. (May 2018) Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discovery, 8 (9). pp. 1112-1129. ISSN 21598274 (Public Dataset)

Conference or Workshop Item

Lan, Wenjun, Sun, Shoujun, Nigri, Jeremy, Homer, Josh, Park, Young, Deschenes, Astrid, Cifani, Paolo, Cross, Justin, Gaeth, Victoria, Kim, Sunny, Ting, Shawn, Rubino, Rachel, Moses, John, Tuveson, David (January 2024) SOAT1 as a targetable KRAS dependency in PDAC. In: AACR Special Conference in Cancer Research: Pancreatic Cancer, 2023 Sep 27-30, Boston, Massachusetts.

Belleau, Pascal, Deschenes, Astrid, Tuveson, David A, Krasnitz, Alexander (2022) Accurate inference of genetic ancestry from cancer-derived data. In: American Association for Cancer Research Annual Meeting 2022, 2022 Apr 8-13, Philadelphia, PA.

Yang, Jung-In, Ha, Taehoon, Zhou, Edward, Tzanavaris, Chris, Deschenes, Astrid, Boyd, Jeff, Hollweg, Christopher, Zhu, Xinhua, King, Daniel (2022) GATA6 amplification is associated with improved survival of TP53-mutated pancreatic cancer. In: UNSPECIFIED.

Belleau, Pascal, Deschenes, Astrid, Tuveson, David A, Krasnitz, Alexander (2022) Reliable determination of genetic ancestry from cancer-derived molecular data. In: Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), JUN 03-07, 2022.

Tonelli, Claudia, Yordanov, Georgi N, Hao, Yuan, Deschenes, Astrid, Brosnan, Erin, Doshi, Abishek, Park, Youngkyu, Preall, Jonathan, Tuveson, David A (2022) The transcription factor SPDEF promotes the survival of mucinous pancreatic ductal adenocarcinoma of the classical subtype. In: American Association for Cancer Research Annual Meeting 2022, 2022 Apr 8-13, Philadelphia, PA.