Microwave-Enhanced Reaction of Thioacids with Azides in Aqueous Medium

Sharma, Pallavi, Moorhouse, Adam D, Moses, John E (October 2011) Microwave-Enhanced Reaction of Thioacids with Azides in Aqueous Medium. Synlett: accounts and rapid communications in synthetic organic chemistry, 2011 (16). pp. 2384-2386. ISSN 0936-5214

URL: https://www.thieme-connect.de/products/ejournals/a...
DOI: 10.1055/s-0030-1261236


An efficient entry to aromatic amides using microwave irradiation in aqueous medium is described. Starting from substituted anilines, in situ formation of the corresponding aromatic azide is followed by their immediate reaction with a thioacid to yield amides in excellent yield. This improved protocol significantly reduces the reaction time thus increasing the overall efficiency of this useful transformation. © Georg Thieme Verlag Stuttgart - New York.

Item Type: Paper
Subjects: chemistry > chemicals > aromatic azides
chemistry > techniques > click chemistry
chemistry > techniques > microwaves
chemistry > chemicals > thio acids
CSHL Authors:
SWORD Depositor: CSHL Elements
Depositing User: CSHL Elements
Date: October 2011
Date Deposited: 02 Jul 2021 14:21
Last Modified: 02 Jul 2021 14:21
Related URLs:
URI: https://repository.cshl.edu/id/eprint/40242

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