Migration of CXCR6+ activated/memory T-cells is stopped in response to hypoxia.

Egeblad, M., Nakasone, E. S., Werb, Z. (2010) Migration of CXCR6+ activated/memory T-cells is stopped in response to hypoxia. [Video]

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Abstract

Migration of CXCR6+ activated/memory T-cells is stopped in response to hypoxia. T-cells (green) are seen migrating in a live MMTV-PyMT;ACTB-ECFP;CXCR6EGFP mouse. The same field is shown during normoxia (21% inhaled oxygen), hypoxia (7% inhaled oxygen) and re-established normoxia (21% oxygen). Cancer cells are labeled blue. From Egeblad et al. (2010) Dev. Cell, 18 884-901.

Item Type:	Video
Subjects:	diseases & disorders > cancer diseases & disorders Investigative techniques and equipment organs, tissues, organelles, cell types and functions > cell types and functions > cell types > T cells organs, tissues, organelles, cell types and functions > cell types and functions > cell types > T cells organs, tissues, organelles, cell types and functions > cell types and functions > cell types > T cells organs, tissues, organelles, cell types and functions > cell types and functions > cell types organs, tissues, organelles, cell types and functions > cell types and functions > cell types organs, tissues, organelles, cell types and functions > cell types and functions > cell types organs, tissues, organelles, cell types and functions > cell types and functions Investigative techniques and equipment > microscopy > flourescence microscopy Investigative techniques and equipment > microscopy > immunoflourescence microscopy Investigative techniques and equipment > microscopy organs, tissues, organelles, cell types and functions
CSHL Authors:	Egeblad, Mikala Nakasone, Elizabeth S.
Communities:	CSHL labs > Egeblad lab
Depositing User:	Matt Covey
Date:	2010
Date Deposited:	26 Apr 2013 16:32
Last Modified:	26 Apr 2013 16:32
Related URLs:	Author
URI:	https://repository.cshl.edu/id/eprint/28266

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