High-Resolution Array-Based Comparative Genome Hybridization (CGH) Identifies Novel and Recurrent Regions in CLL

Grubor, V., Krasnitz, A., Troge, J. E., Meth, J. L., Lakshmi, B., Kendall, J. T., Yamrom, B., Alex, G., Pai, D., Navin, N. E., Hufnagel, L. A., Lee, Y. H., Cook, K., Allen, S. L., Rai, K. R., Damle, R., Calissano, C., Chiorazzi, N., Wigler, M. H., Esposito, D. (November 2008) High-Resolution Array-Based Comparative Genome Hybridization (CGH) Identifies Novel and Recurrent Regions in CLL. Blood, 112 (11). p. 717. ISSN 0006-4971

Abstract

Although we have some understanding of the genetic abnormalities occurring in B-cell chronic lymphocytic leukemia (CLL) and their association with clinical outcomes, there is an incomplete comprehension of all of the mutations contributing to disease development and progression. In most abnormalities previously observed, it has been difficult to pinpoint specific candidate genes, reflecting the inadequacy of present tools for assessing chromosomal damage.

Item Type:	Paper
Additional Information:	Meeting Abstract
Subjects:	Investigative techniques and equipment > comparative genomic hybridization Investigative techniques and equipment > assays > comparative genomic hybridization Investigative techniques and equipment Investigative techniques and equipment > assays Publication Type > Meeting Abstract
CSHL Authors:	Alex, Garrick Cook, Kerry Esposito, Diane Grubor, Vladimir Hufnagel, Lisa A. Kendall, Jude T. Krasnitz, Alexander Lakshmi, Balasubramanian Lee, Yoon-Ha Meth, Jennifer L. Navin, Nicholas E. Pai. Deepa Troge, Jennifer E. Wigler, Michael H. Yamrom, Boris
Communities:	CSHL labs > Wigler lab School of Biological Sciences > Publications
Depositing User:	Matt Covey
Date:	November 2008
Date Deposited:	26 Feb 2013 19:54
Last Modified:	07 Jan 2019 19:25
URI:	https://repository.cshl.edu/id/eprint/27542

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