Molecular biology. All packed up and ready to go.

Jacob, Y., Martienssen, R. (2012) Molecular biology. All packed up and ready to go. Science, 336 (6087). pp. 1391-1392. ISSN 0036-8075

URL: http://www.ncbi.nlm.nih.gov/pubmed/22700909
DOI: 10.1126/science.1224272

Abstract

In eukaryotes, the two states of chromatin were first distinguished cytologically according to their different levels of condensation. Euchromatin has an open conformation that correlates with an active state of gene expression, whereas the transcriptionally silent heterochromatin is tightly packaged. On page 1448 of this issue, Moissiard et al. describe the identification of proteins that are specifically required for the condensed structure of heterochromatin in flowering plants (1). And on page 1445 of this issue, Qian et al. (2) identify a plant protein that binds to biochemically modified DNA and itself modifies histones to generate a chromatin state that allows active DNA demethylation (and gene expression).

Item Type: Paper
Uncontrolled Keywords: directed dna methylation organization pathway genome
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > DNA methylation
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > Chromatin dynamics
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > Chromatin dynamics > heterochromatin
CSHL Authors:
Communities: CSHL labs > Martienssen lab
Depositing User: Matt Covey
Date Deposited: 13 Dec 2013 16:50
Last Modified: 13 Dec 2013 16:50
Related URLs:
URI: http://repository.cshl.edu/id/eprint/28979

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