Comparative population genomics of maize domestication and improvement

Hufford, M. B., Xu, X., van Heerwaarden, J., Pyhajarvi, T., Chia, J. M., Cartwright, R. A., Elshire, R. J., Glaubitz, J. C., Guill, K. E., Kaeppler, S. M., Lai, J. S., Morrell, P. L., Shannon, L. M., Song, C., Springer, N. M., Swanson-Wagner, R. A., Tiffin, P., Wang, J., Zhang, G. Y., Doebley, J., McMullen, M. D., Ware, D., Buckler, E. S., Yang, S., Ross-Ibarra, J. (July 2012) Comparative population genomics of maize domestication and improvement. Nature Genetics, 44 (7). pp. 808-811. ISSN 1061-4036

URL: http://www.ncbi.nlm.nih.gov/pubmed/22660546
DOI: 10.1038/ng.2309

Abstract

Domestication and plant breeding are ongoing 10,000-year-old evolutionary experiments that have radically altered wild species to meet human needs. Maize has undergone a particularly striking transformation. Researchers have sought for decades to identify the genes underlying maize evolution(1,2), but these efforts have been limited in scope. Here, we report a comprehensive assessment of the evolution of modern maize based on the genome-wide resequencing of 75 wild, landrace and improved maize lines(3). We find evidence of recovery of diversity after domestication, likely introgression from wild relatives, and evidence for stronger selection during domestication than improvement. We identify a number of genes with stronger signals of selection than those previously shown to underlie major morphological changes(4,5). Finally, through transcriptome-wide analysis of gene expression, we find evidence both consistent with removal of cis-acting variation during maize domestication and improvement and suggestive of modern breeding having increased dominance in expression while targeting highly expressed genes.

Item Type: Paper
Uncontrolled Keywords: arabidopsis seeds rice gene selection patterns diversity origin polymorphism expression evolution
Subjects: Investigative techniques and equipment > comparative genomic hybridization
Investigative techniques and equipment > assays > comparative genomic hybridization

bioinformatics > genomics and proteomics
organism description > plant > maize
organism description > plant
CSHL Authors:
Communities: CSHL labs > Ware lab
Depositing User: Matt Covey
Date: July 2012
Date Deposited: 30 Jan 2013 21:08
Last Modified: 30 Jan 2013 21:08
Related URLs:
URI: http://repository.cshl.edu/id/eprint/26966

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving