The cellular organization of gene expression

Misteli, T., Spector, D. L. (1998) The cellular organization of gene expression. Current Opinion in Cell Biology, 10. pp. 323-331. ISSN 0955-0674

URL: http://www.ncbi.nlm.nih.gov/pubmed/9640532
DOI: 10.1016/S0955-0674(98)80007-0

Abstract

Recent cell biological observations have provided new insights into how transcription, pre-mRNA splicing and 3' processing are organized and coordinated with each other in the mammalian cell nucleus. Morphological observations are supported by biochemical evidence that suggests physical interactions between components of the transcription and RNA processing machineries. A working model of the cellular organization of gene expression is now emerging.

Item Type: Paper
Uncontrolled Keywords: Animals Cell Compartmentation Cell Nucleus Gene Expression Regulation RNA Splicing
Subjects: organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > cell organization
organs, tissues, organelles, cell types and functions > cell types and functions
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > gene expression
CSHL Authors:
Communities: CSHL labs > Spector lab
Depositing User: Matt Covey
Date Deposited: 10 Dec 2012 19:57
Last Modified: 29 Jan 2015 17:24
Related URLs:
URI: http://repository.cshl.edu/id/eprint/26343

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