Items where Subject is "CRISPR-Cas9"

Paper

Bell, C. C., Fennell, K. A., Chan, Y. C., Rambow, F., Yeung, M. M., Vassiliadis, D., Lara, L., Yeh, P., Martelotto, L. G., Rogiers, A., Kremer, B. E., Barbash, O., Mohammad, H. P., Johanson, T. M., Burr, M. L., Dhar, A., Karpinich, N., Tian, L., Tyler, D. S., MacPherson, L., Shi, J., Pinnawala, N., Yew Fong, C., Papenfuss, A. T., Grimmond, S. M., Dawson, S. J., Allan, R. S., Kruger, R. G., Vakoc, C. R., Goode, D. L., Naik, S. H., Gilan, O., Lam, E. Y. N., Marine, J. C., Prinjha, R. K., Dawson, M. A. (June 2019) Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia. Nat Commun, 10 (1). p. 2723. ISSN 2041-1723

Bharathy, N., Berlow, N. E., Wang, E., Abraham, J., Settelmeyer, T. P., Hooper, J. E., Svalina, M. N., Bajwa, Z., Goros, M. W., Hernandez, B. S., Wolff, J. E., Pal, R., Davies, A. M., Ashok, A., Bushby, D., Mancini, M., Noakes, C., Goodwin, N. C., Ordentlich, P., Keck, J., Hawkins, D. S., Rudzinski, E. R., Mansoor, A., Perkins, T. J., Vakoc, C. R., Michalek, J. E., Keller, C. (May 2019) Preclinical rationale for entinostat in embryonal rhabdomyosarcoma. Skelet Muscle, 9 (1). p. 12. ISSN 2044-5040

Bharathy, Narendra, Cleary, Megan M, Kim, Jin-Ah, Nagamori, Kiyo, Crawford, Kenneth A, Wang, Eric, Saha, Debarya, Settelmeyer, Teagan P, Purohit, Reshma, Skopelitis, Damianos, Chang, Kenneth, Doran, Jessica A, Kirschbaum, C Ward, Bharathy, Suriya, Crews, Davis W, Randolph, Matthew E, Karnezis, Anthony N, Hudson-Price, Lisa, Dhawan, Jyotsna, Michalek, Joel E, Ciulli, Alessio, Vakoc, Christopher R, Keller, Charles (January 2022) SMARCA4 biology in alveolar rhabdomyosarcoma. Oncogene. ISSN 0950-9232

Bottcher, J., Dilworth, D., Reiser, U., Neumuller, R. A., Schleicher, M., Petronczki, M., Zeeb, M., Mischerikow, N., Allali-Hassani, A., Szewczyk, M. M., Li, F., Kennedy, S., Vedadi, M., Barsyte-Lovejoy, D., Brown, P. J., Huber, K. V. M., Rogers, C. M., Wells, C. I., Fedorov, O., Rumpel, K., Zoephel, A., Mayer, M., Wunberg, T., Bose, D., Zahn, S., Arnhof, H., Berger, H., Reiser, C., Hormann, A., Krammer, T., Corcokovic, M., Sharps, B., Winkler, S., Haring, D., Cockcroft, X. L., Fuchs, J. E., Mullauer, B., Weiss-Puxbaum, A., Gerstberger, T., Boehmelt, G., Vakoc, C. R., Arrowsmith, C. H., Pearson, M., McConnell, D. B. (July 2019) Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3. Nat Chem Biol, 15 (8). pp. 822-829. ISSN 1552-4450

Brien, G. L., Remillard, D., Shi, J., Hemming, M. L., Chabon, J., Wynne, K., Dillon, E. T., Cagney, G., Van Mierlo, G., Baltissen, M. P., Vermeulen, M., Qi, J., Frohling, S., Gray, N. S., Bradner, J. E., Vakoc, C. R., Armstrong, S. A. (November 2018) Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma. Elife, 7. ISSN 2050-084x

Castel, S. E., Cervera, A., Mohammadi, P., Aguet, F., Reverter, F., Wolman, A., Guigo, R., Iossifov, I., Vasileva, A., Lappalainen, T. (August 2018) Modified penetrance of coding variants by cis-regulatory variation contributes to disease risk. Nat Genet, 50 (9). pp. 1327-1334. ISSN 1061-4036

Chen, C. C., Li, B., Millman, S. E., Chen, C., Li, X., Morris, J. P. Iv, Mayle, A., Ho, Y. J., Loizou, E., Liu, H., Qin, W., Shah, H., Violante, S., Cross, J. R., Lowe, S. W., Zhang, L. (January 2020) Vitamin B6 Addiction in Acute Myeloid Leukemia. Cancer Cell, 37 (1). pp. 71-84. ISSN 15356108 (ISSN) (Public Dataset)

Chou, Hsiang-Chen, Bhalla, Kuhulika, Demerdesh, Osama El, Klingbeil, Olaf, Hanington, Kaarina, Aganezov, Sergey, Andrews, Peter, Alsudani, Habeeb, Chang, Kenneth, Vakoc, Christopher R, Schatz, Michael C, McCombie, W Richard, Stillman, Bruce (February 2021) The human Origin Recognition Complex is essential for pre-RC assembly, mitosis and maintenance of nuclear structure. eLife, 10. ISSN 2050-084X

Costa, Iris Munhoz, Effer, Brian, Costa-Silva, Tales Alexandre, Chen, Chen, Ciccone, Michael F, Pessoa, Adalberto, Dos Santos, Camila O, Monteiro, Gisele (July 2023) Cathepsin B Is Not an Intrinsic Factor Related to Asparaginase Resistance of the Acute Lymphoblastic Leukemia REH Cell Line. International Journal of Molecular Sciences, 24 (13). p. 11215. ISSN 1661-6596

Ehrenhofer-Wolfer, K., Puchner, T., Schwarz, C., Rippka, J., Blaha-Ostermann, S., Strobl, U., Hormann, A., Bader, G., Kornigg, S., Zahn, S., Sommergruber, W., Schweifer, N., Zichner, T., Schlattl, A., Neumuller, R. A., Shi, J., Vakoc, C. R., Kogl, M., Petronczki, M., Kraut, N., Pearson, M. A., Wohrle, S. (August 2019) SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines. Sci Rep, 9 (1). p. 11661. ISSN 2045-2322

Ely, Zackery A, Mathey-Andrews, Nicolas, Naranjo, Santiago, Gould, Samuel I, Mercer, Kim L, Newby, Gregory A, Cabana, Christina M, Rideout, William M, Jaramillo, Grissel Cervantes, Khirallah, Jennifer M, Holland, Katie, Randolph, Peyton B, Freed-Pastor, William A, Davis, Jessie R, Kulstad, Zachary, Westcott, Peter MK, Lin, Lin, Anzalone, Andrew V, Horton, Brendan L, Pattada, Nimisha B, Shanahan, Sean-Luc, Ye, Zhongfeng, Spranger, Stefani, Xu, Qiaobing, Sánchez-Rivera, Francisco J, Liu, David R, Jacks, Tyler (May 2023) A prime editor mouse to model a broad spectrum of somatic mutations in vivo. Nature Biotechnology. ISSN 1087-0156 (Public Dataset)

Erard, Nicolas, Knott, Simon R. V., Hannon, Gregory J. (2017) A CRISPR Resource for Individual, Combinatorial, or Multiplexed Gene Knockout. Molecular Cell, 67 (2). 348-354.e3. ISSN 1097-2765

Fiskus, Warren, Mill, Christopher P, Birdwell, Christine, Davis, John A, Das, Kaberi, Boettcher, Steffen, Kadia, Tapan M, DiNardo, Courtney D, Takahashi, Koichi, Loghavi, Sanam, Soth, Michael J, Heffernan, Tim, McGeehan, Gerard M, Ruan, Xinjia, Su, Xiaoping, Vakoc, Christopher R, Daver, Naval, Bhalla, Kapil N (April 2023) Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1. Blood Cancer Journal, 13 (1). p. 53. ISSN 2044-5385 (Public Dataset)

Foronda, M., Tarumoto, Y., Schatoff, E. M., Leach, B. I., Diaz, B. J., Zimmerman, J., Goswami, S., Shusterman, M., Vakoc, C. R., Dow, L. E. (December 2019) Tankyrase inhibition sensitizes cells to CDK4 blockade. PLoS One, 14 (12). e0226645. ISSN 1932-6203

Gao, Yuan, He, Xue-Yan, Wu, Xiaoli S, Huang, Yu-Han, Toneyan, Shushan, Ha, Taehoon, Ipsaro, Jonathan J, Koo, Peter K, Joshua-Tor, Leemor, Bailey, Kelly M, Egeblad, Mikala, Vakoc, Christopher R (January 2023) ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation. Nature Cell Biology. ISSN 1465-7392 (Public Dataset)

Ghosh, D., Venkataramani, P., Nandi, S., Bhattacharjee, S. (January 2019) CRISPR-Cas9 a boon or bane: the bumpy road ahead to cancer therapeutics. Cancer Cell Int, 19. p. 12. ISSN 1475-2867 (Print)1475-2867

Girish, Vishruth, Sheltzer, Jason M (July 2020) A CRISPR Competition Assay to Identify Cancer Genetic Dependencies. Bio-protocol, 10 (14). e3682. ISSN 2331-8325

Giuliano, C. J., Lin, A., Girish, V., Sheltzer, J. M. (August 2019) Generating Single Cell–Derived Knockout Clones in Mammalian Cells with CRISPR/Cas9. Current Protocols in Molecular Biology, 128 (1). Art number e100. ISSN 19343639 (ISSN)

Giuliano, C. J., Lin, A., Smith, J. C., Palladino, A. C., Sheltzer, J. M. (July 2018) Combining CRISPR/Cas9 mutagenesis and a small-molecule inhibitor to probe the function of MELK in cancer. Cancer Research, 78 (13 S). Meeting Abstract: 837A . ISSN 0008-5472

Giuliano, C. J., Lin, A., Smith, J. C., Palladino, A. C., Sheltzer, J. M. (February 2018) MELK expression correlates with tumor mitotic activity but is not required for cancer growth. Elife, 7. ISSN 2050-084x

Giuliano, C. J., Lin, A., Girish, V., Sheltzer, J. M. (September 2019) Generating Single Cell-Derived Knockout Clones in Mammalian Cells with CRISPR/Cas9. Curr Protoc Mol Biol, 128 (1). e100. ISSN 1934-3639 (Print)1934-3647

Gutbrod, MJ, Roche, B, Steinberg, JI, Lakhani, AA, Chang, K, Schorn, AJ, Martienssen, RA (February 2022) Dicer promotes genome stability via the bromodomain transcriptional co-activator BRD4. Nature Communications, 13 (1). p. 1001. ISSN 2041-1723

He, Jia, Alonge, Michael, Ramakrishnan, Srividya, Benoit, Matthias, Soyk, Sebastian, Reem, Nathan, Hendelman, Anat, Eck, Joyce Van, Schatz, Michael, Lippman, Zachary (2022) Establishing Physalisas a new Solanaceae model system enables genetic reevaluation of the inflated calyx syndrome. bioRxiv. (Submitted)

Hendelman, Anat, Zebell, Sophia, Rodriguez-Leal, Daniel, Dukler, Noah, Robitaille, Gina, Wu, Xuelin, Kostyun, Jamie, Tal, Lior, Wang, Peipei, Bartlett, Madelaine E, Eshed, Yuval, Efroni, Idan, Lippman, Zachary B (April 2021) Conserved pleiotropy of an ancient plant homeobox gene uncovered by cis-regulatory dissection. Cell, 184 (7). 1724-1739.e16. ISSN 0092-8674

Hutton, Elizabeth, Vakoc, Christopher, Siepel, Adam (December 2019) ACE: A Probabilistic Model for Characterizing Gene-Level Essentiality in CRISPR Screens. bioRxiv.

Hutton, Elizabeth R, Vakoc, Christopher R, Siepel, Adam (September 2021) ACE: a probabilistic model for characterizing gene-level essentiality in CRISPR screens. Genome Biology, 22 (1). p. 278. ISSN 1474-760X

Hörmann, A., Hopfgartner, B., Köcher, T., Corcokovic, M., Krammer, T., Reiser, C., Bader, G., Shi, J., Ehrenhöfer, K., Wöhrle, S., Schweifer, N., Vakoc, C. R., Kraut, N., Pearson, M., Petronczki, M., Neumüller, R. A. (June 2018) RIOK1 kinase activity is required for cell survival irrespective of MTAP status. Oncotarget, 9 (47). pp. 28625-28637. ISSN 1949-2553

Ipsaro, J. J., Shen, C., Arai, E., Xu, Y., Kinney, J. B., Joshua-Tor, L., Vakoc, C. R., Shi, J. (February 2017) Rapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis. PLoS One, 12 (2). e0172177. ISSN 1932-6203

Kakeshpour, T., Wu, Q., Tamang, T., Park, J., Park, S. (June 2018) Multiplex Genome Editing of Class II Glutaredoxins in Solanum lycopersicum Via a CRISPR/Cas9 System. In Vitro Cellular & Developmental Biology-Animal, 54 (Supple). S46-S47. ISSN 1071-2690

Klingbeil, Olaf, Skopelitis, Damianos, Tonelli, Claudia, Alpsoy, Aktan, Minicozzi, Francesca, Aggarwal, Disha, Russo, Suzanne, Ha, Taehoon, Demerdash, Osama E, Spector, David L, Tuveson, David A, Cifani, Paolo, Vakoc, Christopher R (February 2024) MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer. bioRxiv. (Submitted)

Krause, William C, Rodriguez, Ruben, Gegenhuber, Bruno, Matharu, Navneet, Rodriguez, Andreas N, Padilla-Roger, Adriana M, Toma, Kenichi, Herber, Candice B, Correa, Stephanie M, Duan, Xin, Ahituv, Nadav, Tollkuhn, Jessica, Ingraham, Holly A (October 2021) Oestrogen engages brain MC4R signalling to drive physical activity in female mice. Nature. ISSN 0028-0836

Kwon, C. T., Heo, J., Lemmon, Z. H., Capua, Y., Hutton, S. F., Van Eck, J., Park, S. J., Lippman, Z. B. (December 2019) Rapid customization of Solanaceae fruit crops for urban agriculture. Nat Biotechnol, 38. pp. 182-188. ISSN 1087-0156

Lan, X., Khandros, E., Huang, P., Peslak, S. A., Bhardwaj, S. K., Grevet, J. D., Abdulmalik, O., Wang, H., Keller, C. A., Giardine, B., Baeza, J., Duffner, E. R., El Demerdash, O., Wu, X. S., Vakoc, C. R., Garcia, B. A., Hardison, R. C., Shi, J., Blobel, G. A. (May 2019) The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells. Blood Adv, 3 (10). pp. 1586-1597. ISSN 2473-9529

Lanning, B. R., Vakoc, C. R. (April 2017) Single-minded CRISPR screening. Nat Biotechnol, 35 (4). pp. 339-340. ISSN 1087-0156

Lemmon, Z. H., Reem, N. T., Dalrymple, J., Soyk, S., Swartwood, K. E., Rodriguez-Leal, D., Van Eck, J., Lippman, Z. B. (October 2018) Rapid improvement of domestication traits in an orphan crop by genome editing. Nature Plants, 4 (10). pp. 766-770. ISSN 20550278 (ISSN)

Li, Bin E, Li, Grace Y, Cai, Wenqing, Zhu, Qian, Seruggia, Davide, Fujiwara, Yuko, Vakoc, Christopher R, Orkin, Stuart (July 2023) In vivo CRISPR/Cas9 Screening Identifies Pbrm1 as a Regulator of Mouse Myeloid Leukemia Development. Blood Advances, 7 (18). pp. 5281-5293. ISSN 2473-9529 (Public Dataset)

Li, Jin-Jing, Lin, Xiang, Tang, Cheng, Lu, Ying-Qian, Hu, Xinde, Zuo, Erwei, Li, He, Ying, Wenqin, Sun, Yidi, Lai, Lu-Lu, Chen, Hai-Zhu, Guo, Xin-Xin, Zhang, Qi-Jie, Wu, Shuang, Zhou, Changyang, Shen, Xiaowen, Wang, Qifang, Lin, Min-Ting, Ma, Li-Xiang, Wang, Ning, Krainer, Adrian R, Shi, Linyu, Yang, Hui, Chen, Wan-Jin (January 2020) Disruption of splicing-regulatory elements using CRISPR/Cas9 to rescue spinal muscular atrophy in human iPSCs and mice. National Science Review, 7 (1). pp. 92-101. ISSN 2095-5138

Li, Ruitong, Klingbeil, Olaf, Monducci, Davide, Young, Michael J, Rodriguez, Diego J, Bayyat, Zaid, Dempster, Joshua M, Kesar, Devishi, Yang, Xiaoping, Zamanighomi, Mahdi, Vakoc, Christopher R, Ito, Takahiro, Sellers, William R (May 2022) Comparative optimization of combinatorial CRISPR screens. Nature Communications, 13 (1). p. 2469. ISSN 2041-1723

Lin, A., Giuliano, C. J., Palladino, A., John, K. M., Abramowicz, C., Yuan, M. L., Sausville, E. L., Lukow, D. A., Liu, L., Chait, A. R., Galluzzo, Z. C., Tucker, C., Sheltzer, J. M. (September 2019) Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials. Sci Transl Med, 11 (509). ISSN 1946-6234

Lin, A., Giuliano, C. J., Sayles, N. M., Sheltzer, J. M. (March 2017) CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials. Elife, 6. e24179. ISSN 2050-084x

Liu, H., Jian, L., Xu, J., Zhang, Q., Zhang, M., Jin, M., Peng, Y., Yan, J., Han, B., Liu, J., Gao, F., Liu, X., Huang, L., Wei, W., Ding, Y., Yang, X., Li, Z., Zhang, M., Sun, J., Bai, M., Song, W., Chen, H., Sun, X., Li, W., Lu, Y., Liu, Y., Zhao, J., Qian, Y., Jackson, D., Fernie, A.R., Yan, J. (May 2020) High-Throughput CRISPR/Cas9 Mutagenesis Streamlines Trait Gene Identification in Maize. Plant Cell, 32 (5). pp. 1397-1413. ISSN 1040-4651

Liu, Lei, Gallagher, Joseph, Arevalo, Edgar Demesa, Chen, Richelle, Skopelitis, Tara, Wu, Qingyu, Bartlett, Madelaine, Jackson, David (March 2021) Enhancing grain-yield-related traits by CRISPR-Cas9 promoter editing of maize CLE genes. Nature Plants, 7 (3). pp. 287-294. ISSN 2055-026X

Lyons, Scott K, Plenker, Dennis, Trotman, Lloyd C (July 2021) Advances in preclinical evaluation of experimental antibody-drug conjugates. Cancer Drug Resistance, 4. pp. 745-754. ISSN 2578-532X

Maia-Silva, Diogo, Schier, Allison C, Skopelitis, Damianos, Kechejian, Vahag, Alpsoy, Aktan, Liverpool, Jynelle, Taatjes, Dylan J, Vakoc, Christopher R (October 2023) Marker-based CRISPR screening reveals a MED12-p63 interaction that activates basal identity in pancreatic ductal adenocarcinoma. bioRxiv. (Submitted)

Mou, Haiwei, Eskiocak, Onur, Özler, Kadir A, Gorman, Megan, Yue, Junjiayu, Jin, Ying, Wang, Zhikai, Gao, Ya, Janowitz, Tobias, Meyer, Hannah V, Yu, Tianxiong, Wilkinson, John E, Kucukural, Alper, Ozata, Deniz M, Beyaz, Semir (January 2023) CRISPR-induced exon skipping of β-catenin reveals tumorigenic mutants driving distinct subtypes of liver cancer. Journal of Pathology. ISSN 0022-3417

Polyanskaya, Sofya A, Moreno, Rosamaria Y, Lu, Bin, Feng, Ruopeng, Yao, Yu, Irani, Seema, Klingbeil, Olaf, Yang, Zhaolin, Wei, Yiliang, Demerdash, Osama E, Benjamin, Lukas A, Weiss, Mitchell J, Zhang, Yan Jessie, Vakoc, Christopher R (January 2022) SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia. Cell Reports, 38 (2). p. 110233. ISSN 2211-1247

Rodríguez-Leal, Daniel, Lemmon, Zachary H., Man, Jarrett, Bartlett, Madelaine E., Lippman, Zachary B. (October 2017) Engineering Quantitative Trait Variation for Crop Improvement by Genome Editing. Cell, 171 (2). pp. 470-80. ISSN 0092-8674

Rogava, Meri, Aprati, Tyler J, Chi, Wei-Yu, Melms, Johannes C, Hug, Clemens, Davis, Stephanie H, Earlie, Ethan M, Chung, Charlie, Deshmukh, Sachin K, Wu, Sharon, Sledge, George, Tang, Stephen, Ho, Patricia, Amin, Amit Dipak, Caprio, Lindsay, Gurjao, Carino, Tagore, Somnath, Ngo, Bryan, Lee, Michael J, Zanetti, Giorgia, Wang, Yiping, Chen, Sean, Ge, William, Melo, Luiza Martins Nascentes, Allies, Gabriele, Rösler, Jonas, Gibney, Goeffrey T, Schmitz, Oliver J, Sykes, Megan, Creusot, Rémi J, Tüting, Thomas, Schadendorf, Dirk, Röcken, Martin, Eigentler, Thomas K, Molotkov, Andrei, Mintz, Akiva, Bakhoum, Samuel F, Beyaz, Semir, Cantley, Lewis C, Sorger, Peter K, Meckelmann, Sven W, Tasdogan, Alpaslan, Liu, David, Laughney, Ashley M, Izar, Benjamin (January 2024) Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature Cancer. ISSN 2662-1347 (Public Dataset)

Senturk, S., Shirole, N. H., Nowak, D. G., Corbo, V., Pal, D., Vaughan, A., Tuveson, D. A., Trotman, L. C., Kinney, J. B., Sordella, R. (February 2017) Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization. Nat Commun, 8. p. 14370. ISSN 2041-1723 (Public Dataset)

Seo, Myeong-Gyun, Lim, Yoonseo, Hendelman, Anat, Robitaille, Gina, Beak, Hong Kwan, Hong, Woo-Jong, Park, Soon Ju, Lippman, Zachary B, Park, Young-Joon, Kwon, Choon-Tak (June 2024) Evolutionary conservation of receptor compensation for stem cell homeostasis in Solanaceae plants. Horticulture Research, 11 (6). uhae126. ISSN 2662-6810 (Public Dataset)

Sher, Falak, Hossain, Mir, Seruggia, Davide, Schoonenberg, Vivien AC, Yao, Qiuming, Cifani, Paolo, Dassama, Laura MK, Cole, Mitchel A, Ren, Chunyan, Vinjamur, Divya S, Macias-Trevino, Claudio, Luk, Kevin, McGuckin, Connor, Schupp, Patrick G, Canver, Matthew C, Kurita, Ryo, Nakamura, Yukio, Fujiwara, Yuko, Wolfe, Scot A, Pinello, Luca, Maeda, Takahiro, Kentsis, Alex, Orkin, Stuart H, Bauer, Daniel E (July 2019) Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis. Nature Genetics, 51 (7). pp. 1149-1159. ISSN 1061-4036

Shi, J., Wang, E., Milazzo, J. P., Wang, Z., Kinney, J. B., Vakoc, C. R. (June 2015) Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains. Nat Biotechnol, 33 (6). pp. 661-67. ISSN 1546-1696 (Electronic)1087-0156 (Linking)

Soyk, S., Lemmon, Z. H., Sedlazeck, F. J., Jimenez-Gomez, J. M., Alonge, M., Hutton, S. F., Van Eck, J., Schatz, M. C., Lippman, Z. B. (May 2019) Duplication of a domestication locus neutralized a cryptic variant that caused a breeding barrier in tomato. Nat Plants, 5 (5). pp. 471-497. ISSN 2055-0278

Sun, Qingtao, van de Lisdonk, Daniëlle, Ferrer, Miriam, Gegenhuber, Bruno, Wu, Melody, Tollkuhn, Jessica, Janowitz, Tobias, Li, Bo (January 2023) Area postrema neurons mediate interleukin-6 function in cancer-associated cachexia. bioRxiv. (Unpublished)

Sánchez-Rivera, Francisco J, Diaz, Bianca J, Kastenhuber, Edward R, Schmidt, Henri, Katti, Alyna, Kennedy, Margaret, Tem, Vincent, Ho, Yu-Jui, Leibold, Josef, Paffenholz, Stella V, Barriga, Francisco M, Chu, Kevan, Goswami, Sukanya, Wuest, Alexandra N, Simon, Janelle M, Tsanov, Kaloyan M, Chakravarty, Debyani, Zhang, Hongxin, Leslie, Christina S, Lowe, Scott W, Dow, Lukas E (February 2022) Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants. Nature Biotechnology. ISSN 1087-0156

Tuveson, D., Clevers, H. (June 2019) Cancer modeling meets human organoid technology. Science, 364 (6444). pp. 952-955. ISSN 0036-8075

Vakoc, C. (January 2018) Cancer drug target identification using domain-focused CRISPR screening. Clinical Cancer Research, 24 (2 Supp). p. 19. ISSN 1078-0432

Van Eck, J., Swartwood, K., Lemmon, Z. H., Dalrymple, J., Lippman, Z. B. (June 2017) Development of Agrobacterium-mediated Transformation of Physalis peruviana and Application of CRISPR/Cas9 Genome Editing. In Vitro Cellular & Developmental Biology-Animal, 53 (Supple). S34-S35. ISSN 1071-2690

Wang, E., Lu, S. X., Pastore, A., Chen, X., Imig, J., Chun-Wei Lee, S., Hockemeyer, K., Ghebrechristos, Y. E., Yoshimi, A., Inoue, D., Ki, M., Cho, H., Bitner, L., Kloetgen, A., Lin, K. T., Uehara, T., Owa, T., Tibes, R., Krainer, A. R., Abdel-Wahab, O., Aifantis, I. (February 2019) Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia. Cancer Cell, 35 (3). 359-384.e7. ISSN 1535-6108

Wei, Y. L., Vakoc, C. (July 2019) Probing leukemia vulnerabilities in vivousing domain-focused CRISPR screening. Cancer Research, 79 (13). Meeting Abstract 5161. ISSN 0008-5472

Wu, Q., Xu, F., Liu, L., Char, S. N., Ding, Y., Je, B. I., Schmelz, E., Yang, B., Jackson, D. (December 2019) The maize heterotrimeric G protein beta subunit controls shoot meristem development and immune responses. Proc Natl Acad Sci U S A, 117 (3). pp. 1799-1805. ISSN 0027-8424 (Public Dataset)

Zafra, M. P., Schatoff, E. M., Katti, A., Foronda, M., Breinig, M., Schweitzer, A. Y., Simon, A., Han, T., Goswami, S., Montgomery, E., Thibado, J., Kastenhuber, E. R., Sanchez-Rivera, F. J., Shi, J., Vakoc, C. R., Lowe, S. W., Tschaharganeh, D. F., Dow, L. E. (October 2018) Optimized base editors enable efficient editing in cells, organoids and mice. Nat Biotechnol, 36 (9). pp. 888-896. ISSN 1087-0156

Zebell, S. G. (October 2020) Excising the Mystery of Single-Guide RNA Processing. Plant Physiol, 184 (2). pp. 572-573. ISSN 0032-0889 (Print)0032-0889

Zhou, Jessica, Guruvayurappan, Karthik, Toneyan, Shushan, Chen, Hsiuyi V, Chen, Aaron R, Koo, Peter, McVicker, Graham (July 2024) Analysis of single-cell CRISPR perturbations indicates that enhancers act multiplicatively and provides limited evidence for epistatic-like interactions. bioRxiv. (Public Dataset) (Submitted)

Zhou, Jessica L, Guruvayurappan, Karthik, Toneyan, Shushan, Chen, Hsiuyi V, Chen, Aaron R, Koo, Peter, McVicker, Graham (October 2024) Analysis of single-cell CRISPR perturbations indicates that enhancers predominantly act multiplicatively. Cell Genomics. p. 100672. ISSN 2666-979X (Public Dataset)

Šafarič Tepeš, Polona, Sordella, Raffaella (September 2021) A New Toolkit for Evaluating Gene Functions using Conditional Cas9 Stabilization. Journal of Visualized Experiments (175). ISSN 1940-087X

Book Section

Chung, Taemoon, Merrill, Joseph R, Lyons, Scott K (2024) CRISPR/Cas for PET Reporter Gene Engineering. In: Methods in Molecular Biology. UNSPECIFIED, pp. 285-301. ISBN 9781071634981

Conference or Workshop Item

Iyer, Shruti V, Kramer, Melissa, Goodwin, Sara, McCombie, W Richard (2022) Cas9 based targeted nanopore sequencing helps identify structural variants in breast cancer genes. In: Annual Meeting of the American-Association-for-Cancer-Research (AACR), APR 08-13, 2022, New Orleans, LA.

Van Eck, J, Brooks, C, Nekrasov, V, Lippman, Z (May 2015) Application of CRISPR/Cas9 Technology for Characterization of Developmental Genes in Tomato. In: In Vitro Biology Meeting.

Van Eck, Joyce, Reem, Nathan, Swartwood, Kerry, Shenstone, Esperanza, Williams, Brandon, Lippman, Zachary B (June 2019) Improvement of Goldenberry and Groundcherry by CRISPR: Ripening the Potential of Underutilized Fruit Crops. In: In Vitro Biology Meeting Abstract.

Thesis

Aguirre, Lyndsey (March 2023) Dissection of Quantitative Epistasis in Tomato Meristem Development. PhD thesis, Cold Spring Harbor Laboratory.

Chou, Hsiang-Chen (July 2021) The role of human ORC2 in DNA replication, mitosis and organization of the nucleus. PhD thesis, Cold Spring Harbor Laboratory.

Johnson, David (July 2022) ELUCIDATING THE EFFECTS OF DEPLETING BRPF1 IN HUMAN GBM. PhD thesis, Cold Spring Harbor Laboratory.

Lakhani, Asad A (March 2023) The Role of Recurrently Observed Aneuploidy in Tumorigenesis. PhD thesis, Cold Spring Harbor Laboratory.

Polyanskaya, Sofya A (July 2020) A Nuclear Phosphatase-Kinase Signaling Complex That Supports Acute Myeloid Leukemia. PhD thesis, Cold Spring Harbor Laboratory.