Adam, Nolwenn, Tollkuhn, Jessica (December 2025) Development of the social behavior network. Current Opinion in Neurobiology, 96. p. 103159. ISSN 0959-4388
Abstract
Social behaviors are crucial for reproductive success and survival. In vertebrates, these behaviors are sexually dimorphic due to distinct hormonal environments in development and adulthood. The underlying neural pathways, collectively known as the social behavior network (SBN), consist of interconnected regions exhibiting sex-variable genomic, anatomical, and functional characteristics. While the structure and function of the adult SBN is increasingly well described, its embryonic origins and development remain poorly understood. All neural networks undergo extensive genomic and functional changes during development, but a unique feature of the SBN is its sensitivity to gonadal hormones. Transient developmental hormone signaling ultimately results in anatomic SBN sexual dimorphism and sex-variable behavioral repertoires. However, the precise mechanisms linking early life hormone signaling to the establishment of neural sex differences remain elusive. This review highlights recent findings on SBN development spanning embryonic timepoints to puberty, offering valuable perspectives to address this critical topic.
| Item Type: | Paper |
|---|---|
| Subjects: | organism description > animal behavior organism description > animal behavior > social |
| CSHL Authors: | |
| Communities: | CSHL labs > Tollkuhn lab CSHL Post Doctoral Fellows |
| SWORD Depositor: | CSHL Elements |
| Depositing User: | CSHL Elements |
| Date: | 20 December 2025 |
| Date Deposited: | 05 Jan 2026 15:37 |
| Last Modified: | 05 Jan 2026 15:37 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/42054 |
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