Of hope from fading will: Interoceptive signaling and the behavioral biology of cachexia

Janowitz, Tobias (September 2025) Of hope from fading will: Interoceptive signaling and the behavioral biology of cachexia. Neuron, 113 (17). pp. 2729-2733. ISSN 0896-6273

Abstract

This NeuroView explores how systemic cancer signals induce behavioral changes via brain-body communication pathways, framing cachexia as an adaptive yet unsustainable interoceptive response. Recognizing patient-reported symptoms as biological signals offers new avenues for intervention and understanding brain-disease interactions.

Item Type: Paper
Subjects: diseases & disorders
diseases & disorders > nutritional and metabolic diseases
diseases & disorders > nutritional and metabolic diseases > cachexia
CSHL Authors:
Communities: CSHL Cancer Center Program > Cancer Genetics and Genomics Program
CSHL labs > Janowitz lab
CSHL Cancer Center Program
SWORD Depositor: CSHL Elements
Depositing User: CSHL Elements
Date: September 2025
Date Deposited: 08 Sep 2025 18:46
Last Modified: 08 Sep 2025 18:46
Related URLs:
URI: https://repository.cshl.edu/id/eprint/41955

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