Koh, Kexin, Scott, Rachel, Cespedes Feliciano, Elizabeth M, Janowitz, Tobias, Goncalves, Marcus D, White, Eileen P, Laird, Barry JA, Haase, Kerstin, Jamal-Hanjani, Mariam (April 2025) Cancer-Associated Cachexia: Bridging Clinical Findings with Mechanistic Insights in Human Studies. Cancer Discovery. OF1-OF26. ISSN 2159-8290
Abstract
CAC represents a significant clinical unmet need. Despite its high prevalence and associated mortality and morbidity, there are currently no globally approved effective therapies. This review provides a comprehensive overview of human studies aimed at defining CAC clinically and identifying mediators underlying it that are revealing effective health interventions. Furthermore, we highlight ongoing international efforts to advance our understanding of CAC.
| Item Type: | Paper |
|---|---|
| Subjects: | diseases & disorders diseases & disorders > nutritional and metabolic diseases diseases & disorders > nutritional and metabolic diseases > cachexia |
| CSHL Authors: | |
| Communities: | CSHL labs > Janowitz lab |
| SWORD Depositor: | CSHL Elements |
| Depositing User: | CSHL Elements |
| Date: | 29 April 2025 |
| Date Deposited: | 29 Apr 2025 18:29 |
| Last Modified: | 29 Apr 2025 18:29 |
| URI: | https://repository.cshl.edu/id/eprint/41861 |
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