PTP1B: mediating ROS signaling to silence genes

Boivin, Benoit, Tonks, Nicholas K (2015) PTP1B: mediating ROS signaling to silence genes. Molecular and Cellular Oncology, 2 (2). e975633. ISSN 2372-3556

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URL: https://www.ncbi.nlm.nih.gov/pubmed/27308433

DOI: 10.4161/23723556.2014.975633

Abstract

Numerous studies have shown that normal cells often respond to the activation of oncogenes by undergoing reactive oxygen species-dependent induction of senescence. Here, we discuss our recent publication identifying protein tyrosine phosphatase PTP1B as an important redox-controlled checkpoint for senescence downstream of oncogenic RAS.

Item Type:	Paper
CSHL Authors:	Tonks, Nicholas K.
Communities:	CSHL labs > Tonks lab
SWORD Depositor:	CSHL Elements
Depositing User:	CSHL Elements
Date:	2015
Date Deposited:	28 Oct 2024 19:25
Last Modified:	28 Oct 2024 19:25
PMCID:	PMC4905060
Related URLs:	Publisher
URI:	https://repository.cshl.edu/id/eprint/41720

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