Dai, Enyong, Chen, Xin, Linkermann, Andreas, Jiang, Xuejun, Kang, Rui, Kagan, Valerian E, Bayir, Hülya, Yang, Wan Seok, Garcia-Saez, Ana J, Ioannou, Maria S, Janowitz, Tobias, Ran, Qitao, Gu, Wei, Gan, Boyi, Krysko, Dmitri V, Zhu, Xiaofeng, Wang, Jiayi, Krautwald, Stefan, Toyokuni, Shinya, Xie, Yangchun, Greten, Florian R, Yi, Qing, Schick, Joel, Liu, Jiao, Gabrilovich, Dmitry I, Liu, Jinbao, Zeh, Herbert J, Zhang, Donna D, Yang, Minghua, Iovanna, Juan, Kopf, Manfred, Adolph, Timon E, Chi, Jen-Tsan, Li, Changfeng, Ichijo, Hidenori, Karin, Michael, Sankaran, Vijay G, Zou, Weiping, Galluzzi, Lorenzo, Bush, Ashley I, Li, Binghui, Melino, Gerry, Baehrecke, Eric H, Lotze, Michael T, Klionsky, Daniel J, Stockwell, Brent R, Kroemer, Guido, Tang, Daolin (February 2024) A guideline on the molecular ecosystem regulating ferroptosis. Nature Cell Biology. ISSN 1465-7392
Abstract
Ferroptosis, an intricately regulated form of cell death characterized by uncontrolled lipid peroxidation, has garnered substantial interest since this term was first coined in 2012. Recent years have witnessed remarkable progress in elucidating the detailed molecular mechanisms that govern ferroptosis induction and defence, with particular emphasis on the roles of heterogeneity and plasticity. In this Review, we discuss the molecular ecosystem of ferroptosis, with implications that may inform and enable safe and effective therapeutic strategies across a broad spectrum of diseases.
| Item Type: | Paper |
|---|---|
| Subjects: | diseases & disorders |
| CSHL Authors: | |
| Communities: | CSHL labs > Janowitz lab CSHL Cancer Center Program CSHL Cancer Center Program > Cancer Genetics and Genomics Program |
| SWORD Depositor: | CSHL Elements |
| Depositing User: | CSHL Elements |
| Date: | 29 February 2024 |
| Date Deposited: | 01 Mar 2024 13:41 |
| Last Modified: | 29 Apr 2024 15:49 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/41450 |
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