RNA therapeutics

Hastings, Michelle L, Krainer, Adrian R (April 2023) RNA therapeutics. RNA, 29 (4). pp. 393-395. ISSN 1355-8382

[thumbnail of 2023-Hastings-RNA-therapeutics.pdf] PDF
2023-Hastings-RNA-therapeutics.pdf
Available under License Creative Commons Attribution Non-commercial.
Download (154kB)

Abstract

<jats:p>“RNA therapeutics” refers to a disease treatment or drug that utilizes RNA as a component. In this context, RNA may be the direct target of a small-molecule drug or RNA itself may be the drug, designed to bind to a protein, or to mimic or target another RNA. RNA has gained attention in the drug-development world, as recent clinical successes and breakthrough technologies have revolutionized the drug-like qualities of the molecule or its usefulness as a drug target. In this special issue of<jats:italic>RNA</jats:italic>, we gathered expert perspectives on the past, present, and future of the field, to serve as a primer and also a challenge to the broad scientific community to incorporate RNA into their experimental design and problem-solving process, and to imagine and realize the potential of RNA as a therapeutic drug or target.</jats:p>

Item Type: Paper
Subjects: bioinformatics > genomics and proteomics > analysis and processing
bioinformatics
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
diseases & disorders
bioinformatics > genomics and proteomics > genetics & nucleic acid processing
bioinformatics > genomics and proteomics
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > RNA expression
diseases & disorders > cancer > drugs and therapies
CSHL Authors:
Communities: CSHL labs > Krainer lab
SWORD Depositor: CSHL Elements
Depositing User: CSHL Elements
Date: April 2023
Date Deposited: 28 Mar 2023 18:54
Last Modified: 17 Jan 2025 15:37
PMCID: PMC10019368
Related URLs:
URI: https://repository.cshl.edu/id/eprint/40874

Actions (login required)

Administrator's edit/view item Administrator's edit/view item