RNA therapeutics

Hastings, Michelle L, Krainer, Adrian R (April 2023) RNA therapeutics. RNA, 29 (4). pp. 393-395. ISSN 1355-8382

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Abstract

<jats:p>“RNA therapeutics” refers to a disease treatment or drug that utilizes RNA as a component. In this context, RNA may be the direct target of a small-molecule drug or RNA itself may be the drug, designed to bind to a protein, or to mimic or target another RNA. RNA has gained attention in the drug-development world, as recent clinical successes and breakthrough technologies have revolutionized the drug-like qualities of the molecule or its usefulness as a drug target. In this special issue of<jats:italic>RNA</jats:italic>, we gathered expert perspectives on the past, present, and future of the field, to serve as a primer and also a challenge to the broad scientific community to incorporate RNA into their experimental design and problem-solving process, and to imagine and realize the potential of RNA as a therapeutic drug or target.</jats:p>

Item Type:	Paper
Subjects:	bioinformatics > genomics and proteomics > analysis and processing bioinformatics bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification diseases & disorders bioinformatics > genomics and proteomics > genetics & nucleic acid processing bioinformatics > genomics and proteomics bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > RNA expression diseases & disorders > cancer > drugs and therapies
CSHL Authors:	Krainer, Adrian R.
Communities:	CSHL labs > Krainer lab CSHL Cancer Center Program CSHL Cancer Center Program > Gene Regulation and Inheritance Program
SWORD Depositor:	CSHL Elements
Depositing User:	CSHL Elements
Date:	April 2023
Date Deposited:	28 Mar 2023 18:54
Last Modified:	20 Nov 2024 18:10
PMCID:	PMC10019368
Related URLs:	Publisher
URI:	https://repository.cshl.edu/id/eprint/40874

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