Pouchelon, Gabrielle, Frangeul, Laura, Rijli, Filippo M, Jabaudon, Denis (May 2012) Patterning of pre-thalamic somatosensory pathways. European Journal of Neuroscience, 35 (10). pp. 1533-1539. ISSN 0953-816X
Abstract
The topographical mapping of input is a fundamental organizing principle of sensory pathways. In the somatosensory system, a precise topographical representation of the face is first generated in the brainstem and then faithfully replicated in the thalamus and cortex. Although our knowledge of the distinct polysynaptic pathways that link cutaneous mechanoreceptors of the face with neocortical neurons has recently expanded, the molecular mechanisms controlling their neuron-type-specific assembly during development remain poorly understood. The increasing availability of genetic tools that enable manipulation of these developing circuits with cellular resolution now opens new perspectives in our understanding of the molecular mechanisms through which input from the periphery is converted into patterned central pathways.
| Item Type: | Paper |
|---|---|
| Subjects: | organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons Publication Type > review organs, tissues, organelles, cell types and functions > tissues types and functions > somatosensory cortex organs, tissues, organelles, cell types and functions > tissues types and functions > thalamus organism description > animal behavior > vibrissa motor cortex |
| CSHL Authors: | |
| Communities: | CSHL labs > Pouchelon lab |
| SWORD Depositor: | CSHL Elements |
| Depositing User: | CSHL Elements |
| Date: | May 2012 |
| Date Deposited: | 23 Dec 2021 14:30 |
| Last Modified: | 23 Dec 2021 14:30 |
| URI: | https://repository.cshl.edu/id/eprint/40469 |
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