Navlakha, S., Bar-Joseph, Z. (November 2011) Algorithms in nature: the convergence of systems biology and computational thinking. Mol Syst Biol, 7. p. 546. ISSN 1744-4292
Preview |
PDF
Navlakha_2011_molsbio.pdf - Published Version Download (290kB) | Preview |
Abstract
Computer science and biology have enjoyed a long and fruitful relationship for decades. Biologists rely on computational methods to analyze and integrate large data sets, while several computational methods were inspired by the high-level design principles of biological systems. Recently, these two directions have been converging. In this review, we argue that thinking computationally about biological processes may lead to more accurate models, which in turn can be used to improve the design of algorithms. We discuss the similar mechanisms and requirements shared by computational and biological processes and then present several recent studies that apply this joint analysis strategy to problems related to coordination, network analysis, and tracking and vision. We also discuss additional biological processes that can be studied in a similar manner and link them to potential computational problems. With the rapid accumulation of data detailing the inner workings of biological systems, we expect this direction of coupling biological and computational studies to greatly expand in the future.
| Item Type: | Paper |
|---|---|
| Subjects: | organism description > animal > insect > Drosophila bioinformatics > computational biology > algorithms bioinformatics > computational biology bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > gene network |
| CSHL Authors: | |
| Communities: | CSHL labs > Navlakha lab |
| Depositing User: | Matthew Dunn |
| Date: | 8 November 2011 |
| Date Deposited: | 08 Nov 2019 14:16 |
| Last Modified: | 08 Nov 2019 14:16 |
| PMCID: | PMC3261700 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/38688 |
Actions (login required)
 |
Administrator's edit/view item |