Won, Kwang-Ai, Xiong, Yue, Beach, David, Gilman, Michael Z. (1972) Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts. Proceedings of the National Academy of Sciences of the United States of America, 89 (20). pp. 9910-9914.
Abstract
The human CCND1 cyclin D1/PRAD1 gene was previously identified by a genetic screen for G-1 cyclin function in Saccharomyces cerevisiae and also was identified as the putative BCL1 oncogene. Treatment of HDFs with defined growth factors suggests a correlation between CCND mRNA induction and DNA synthesis. However, induction of these genes is not sufficient for the transition from quiescence through G-1 into S phase.
| Item Type: | Paper |
|---|---|
| Subjects: | organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > cell differentiation |
| CSHL Authors: | |
| Communities: | Cold Spring Harbor Laboratory of Quantitative Biology |
| Depositing User: | Elizabeth Pessala |
| Date: | 1972 |
| Date Deposited: | 15 Apr 2019 17:01 |
| Last Modified: | 15 Apr 2019 17:01 |
| URI: | https://repository.cshl.edu/id/eprint/37340 |
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