Yu, K., Ahrens, S., Zhang, X., Schiff, H., Ramakrishnan, C., Fenno, L., Deisseroth, K., Zhao, F., Luo, M. H., Gong, L., He, M., Zhou, P., Paninski, L., Li, B. (December 2017) The central amygdala controls learning in the lateral amygdala. Nat Neurosci, 20 (12). pp. 1680-1685. ISSN 1097-6256
Abstract
Experience-driven synaptic plasticity in the lateral amygdala is thought to underlie the formation of associations between sensory stimuli and an ensuing threat. However, how the central amygdala participates in such a learning process remains unclear. Here we show that PKC-delta-expressing central amygdala neurons are essential for the synaptic plasticity underlying learning in the lateral amygdala, as they convey information about the unconditioned stimulus to lateral amygdala neurons during fear conditioning.
| Item Type: | Paper |
|---|---|
| Subjects: | organs, tissues, organelles, cell types and functions > tissues types and functions > amygdala organism description > animal behavior > learning |
| CSHL Authors: | |
| Communities: | CSHL labs > Li lab |
| Depositing User: | Matt Covey |
| Date: | December 2017 |
| Date Deposited: | 08 Dec 2017 17:52 |
| Last Modified: | 07 Jul 2021 19:03 |
| PMCID: | PMC5755715 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/35706 |
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