Bonomi, M. R., Misiukiewicz, K., Posner, M., Maki, R. G. (2012) Squamous cell carcinoma of the oral tongue in two patients previously exposed to long-term pegylated liposomal doxorubicin. Oncologist, 17 (12). pp. 1594-5. ISSN 1549-490X (Electronic)1083-7159 (Linking)
Abstract
Pegylated liposomal doxorubicin (PLD) as single agent is being used in different clinical scenarios, including treatment of recurrent epithelial ovarian cancer, HIV-related Kaposi's sarcoma, and desmoid tumors. Prolonged administration has shown a good safety profile [1–3]. Recently, concerns of a higher risk for oral cavity squamous cell carcinoma in patients with a history of prolonged exposure to PLD was reported [4, 5]. We present two cases of oral tongue cancer in patients who never smoked or drank previously but were exposed to PLD.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Adult Carcinoma, Squamous Cell/*chemically induced/pathology Doxorubicin/administration & dosage/adverse effects/*analogs & derivatives Humans Male Middle Aged Polyethylene Glycols/administration & dosage/*adverse effects Tongue Neoplasms/*chemically induced/pathology |
| Subjects: | diseases & disorders > cancer diseases & disorders > cancer > drugs and therapies |
| CSHL Authors: | |
| Communities: | CSHL labs > Maki lab |
| Depositing User: | Matt Covey |
| Date: | 2012 |
| Date Deposited: | 21 Oct 2016 16:29 |
| Last Modified: | 21 Oct 2016 16:29 |
| PMCID: | PMC3528392 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/33727 |
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