Velasco, C. R., Stepansky, A., Dago, A., Carlson, A., Kolatkar, A., Kendall, J., Hicks, J., Kuhn, P. (August 2015) Single-cell molecular profiling of fluid biopsies of epithelial ovarian cancer. Clinical Cancer Research, 21. ISSN 1078-0432
Abstract
The immediate goal of this project is to identify rare circulating tumor cells (CTC) in the bloodstream of epithelial ovarian cancer (EOC) patients and to apply high content, single cell assays that will yield information on morphology, protein expression and genomic structure. The ultimate goal is to develop a minimally invasive “fluid biopsy” for ovarian patients that can provide detailed information on the patient’s response to therapy, early warnings of potential resistance or relapse, and genetic predictors for the most appropriate therapy.
| Item Type: | Paper |
|---|---|
| Additional Information: | Meeting Abstract |
| Subjects: | bioinformatics organs, tissues, organelles, cell types and functions > cell types and functions > cell types > epithelial cell organs, tissues, organelles, cell types and functions > cell types and functions > cell types > epithelial cell organs, tissues, organelles, cell types and functions > cell types and functions > cell types > epithelial cell Publication Type > Meeting Abstract diseases & disorders > cancer > cancer types > ovarian cancer Investigative techniques and equipment > assays > Single cell sequencing |
| CSHL Authors: | |
| Communities: | CSHL labs > Hicks lab CSHL labs > Wigler lab |
| Depositing User: | Matt Covey |
| Date: | August 2015 |
| Date Deposited: | 27 Oct 2015 19:51 |
| Last Modified: | 06 Feb 2018 15:52 |
| URI: | https://repository.cshl.edu/id/eprint/31951 |
Actions (login required)
 |
Administrator's edit/view item |