Hengartner, M. O., Horvitz, H. R. (August 1994) Programmed cell death in Caenorhabditis elegans. Curr Opin Genet Dev, 4 (4). pp. 581-6. ISSN 0959-437X (Print)
Abstract
Programmed cell death in the nematode Caenorhabditis elegans requires the activities of the genes ced-3 and ced-4 and is antagonized by the activity of the gene ced-9. Cloning of these C. elegans genes has shown that two of them encode proteins with similarity to vertebrate cell death genes and has revealed that nematodes and mammals share a common pathway for programmed cell death.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Amino Acid Sequence Animals Apoptosis/ genetics Apoptosis Regulatory Proteins Caenorhabditis elegans/ genetics/ physiology Caenorhabditis elegans Proteins Calcium-Binding Proteins/genetics/physiology Caspases Consensus Sequence Cysteine Proteinase Inhibitors/genetics Genes, Helminth Genes, Viral Helminth Proteins/genetics/physiology Molecular Sequence Data Proto-Oncogene Proteins/genetics/physiology Proto-Oncogene Proteins c-bcl-2 Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Sequence Homology, Amino Acid |
| Subjects: | organism description > animal > C elegans organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > apoptosis |
| CSHL Authors: | |
| Communities: | CSHL labs > Hengartner lab |
| Depositing User: | Matt Covey |
| Date: | August 1994 |
| Date Deposited: | 06 Aug 2015 21:25 |
| Last Modified: | 06 Aug 2015 21:25 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/31423 |
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