Henn, F. A., Henke, D. J. (November 1978) Cellular localization of [3H]-diazepam receptors. Neuropharmacology, 17 (11). pp. 985-8. ISSN 0028-3908 (Print)0028-3908
Abstract
Isolated fractions enriched in bovine cortical astroglial cells or nerve endings were used to determine the receptor site for [3H]-diazepam binding. The results suggest strong enrichment in glial cells for the benzodiazepine receptor. Both the inhibition of diazepam binding by other benzodiazepines and the affinity of the glial receptor for diazepam suggest that this receptor is similar to that previously reported in crude CNS membrane fractions.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Animals Brain/*metabolism Cattle Diazepam/*metabolism Nerve Endings/metabolism Neuroglia/metabolism Receptors, Drug/*analysis |
| Subjects: | organs, tissues, organelles, cell types and functions > cell types and functions > cell types > glia cells organs, tissues, organelles, cell types and functions > cell types and functions > cell types > glia cells organs, tissues, organelles, cell types and functions > cell types and functions > cell types > glia cells bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein receptor |
| CSHL Authors: | |
| Communities: | CSHL labs > Henn lab |
| Depositing User: | Matt Covey |
| Date: | November 1978 |
| Date Deposited: | 09 Jul 2014 15:25 |
| Last Modified: | 09 Jul 2014 15:25 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/30215 |
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