Denk, W., Yuste, R., Svoboda, K., Tank, D. W. (June 1996) Imaging calcium dynamics in dendritic spines. Curr Opin Neurobiol, 6 (3). pp. 372-8. ISSN 0959-4388
Abstract
Recent advances in optical imaging technology have enabled the measurement of Ca2+ dynamics in individual synaptic spines with high time resolution. Results from work using this new technology have confirmed the view that individual synaptic spines can act as functional chemical compartments with independent dynamics of second-messenger concentration. In particular, the ability of Ca2+ to directly mediate Hebbian coincidence detection has been confirmed.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Animals Calcium/*physiology Calcium Channels/physiology Dendrites/*metabolism/physiology/ultrastructure Electrophysiology Microscopy, Fluorescence *Optics Receptors, N-Methyl-D-Aspartate/metabolism Synapses/physiology Technology, Medical |
| Subjects: | organs, tissues, organelles, cell types and functions > cell types and functions > cell types > dendritic cells > dendritic spines organs, tissues, organelles, cell types and functions > cell types and functions > cell types > dendritic cells > dendritic spines organs, tissues, organelles, cell types and functions > cell types and functions > cell types > dendritic cells > dendritic spines |
| CSHL Authors: | |
| Communities: | CSHL labs > Svoboda lab |
| Depositing User: | Matt Covey |
| Date: | June 1996 |
| Date Deposited: | 22 May 2014 14:46 |
| Last Modified: | 22 May 2014 14:46 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/30162 |
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